Sleep deprivation and delirium are closely linked, with shared clinical characteristics, risk factors, and neurochemical abnormalities. Acetylcholine and dopamine are important neurochemicals in the regulation of sleep and wakefulness and their dysregulation has been implicated in development of delirium. In...
Fifteen elderly depressed patients were treated by 36-hour sleep deprivation (SD). The depression was unipolar in 3 cases, bipolar in 3, and secondary in 4. Nine of the 15 patients responded to SD, and 6 had a remission (1 with SD alone and 5 with SD plus an antidepressant drug). ...
Insomnia as a risk factor for onset of depression in the elderly. Behav Sleep Med. 2006;4 (2):104–113. doi:10.1207/s15402010bsm0402_3 10. Alexopoulos GS. Depression in the elderly. Lancet Lond Engl. 2005;365(9475):1961–1970. doi:10.1016/S0140-6736(05)66665-2 11. Bao Y-P, ...
Fifteen elderly depressed patients were treated by 36-hour sleep deprivation (SD). The depression was unipolar in 3 cases, bipolar in 3, and secondary in 4. Nine of the 15 patients responded to SD, and 6 had a remission (1 with SD alone and 5 with SD plus an antidepressant drug). So...
Sleep dysregulation is a feature of dementia but it remains unclear whether sleep duration prior to old age is associated with dementia incidence. Using data from 7959 participants of the Whitehall II study, we examined the association between sleep dura
Sleep deprivation in the AD mouse model produced a substantial increase in Aβ plaque burden.7 We are unaware of any published studies that have investigated whether sleep disturbance is associated with neuroimaging evidence of Aβ deposition in the brains of older living human participants. We ...
Second, some factors, such as daytime sleepiness, depression, and anxiety which also potentially influence PSG changes in AD could not be explored due to limited available data for these variables. Third, it should be noted that obstructive sleep apnea (OSA) may significantly impact sleep [90,...
Response to total sleep deprivation before and during treatment with fluvoxamine or maprotiline in patients with major depression--results of a double-blin... To test the hypothesis that the antidepressant effects of total sleep deprivation (TSD) are linked to the serotonergic and/or noradrenergic ...
Depression beim Parkinson-Syndrom Especially antidepressants, but also sleep deprivation and electroconvulsive therapy are efficient. The review is illustrated by a case report.doi:10.1055/s-2007-996660Haltenhof, HSchrter, CGeorg Thieme Verlag KGFortschr Neurol Psychiatr... Haltenhof, H,Schrter, C ...
On the other hand, sleep deprivation and depression are well known to be mutually reinforcing [56,57,58], and the complex interplay between depression and sleep disorder may engender the deregulation of circadian rhythms by reinforcing negative moods and by decreasing regular exposure to daylight, ...