Circadian rhythmSleep deprivationCircadian misalignmentMicrobiomeGut microbiotaFrom asthma and heart disease to diabetes and obesity, the human microbiome plays a role in the pathogenesis of each chronic health condition plaguing today's society. Recent work has shown that the gut microbiota and its ...
Finally, we discuss the possible interactions between SCRD and GM in AD pathogenesis, as well as several methodological improvements that are necessary for future research. 展开 关键词: Sleep circadian rhythm gut microbiota alzheimers disease animal models inflammation ...
All these events were reversed with the transplantation of SD + melatonin-gut microbiota. Colonization with Aeromonas and the addition of LPS produced an inflammatory response in the hippocampus and spatial memory impairment in mice. These changes were reversed by supplementation with melatonin, ...
Previous studies have shown that sleep disturbances have a significant impact on PLC.2 The International Agency for Research on Cancer (IARC) evaluates the experimental and epidemiological evidence of the link between shift work and various cancers, concluding that circadian rhythm abnormalities can ...
These interactions are known as the “brain–gut axis” or “microbiota–gut–brain axis”9,10. Dysbiosis of the gut microbiota leads to the impairment of brain functions such as memory formation, cognitive function, mental health, and circadian rhythmicity9,11,12,13. Accordingly, the gut ...
Sleep, circadian rhythm and gut microbiota: alterations in Alzheimer's disease and their potential links in the pathogenesis Gut Microbes, 13 (2021), p. 1957407 View in ScopusGoogle Scholar Linde et al., 2011 C.I. Linde, S.G. Baryshnikov, A. Mazzocco-Spezzia, V.A. Golovina Dysregulation...
and learning. Factors discussed here are age, gender, diet, hydration level, obesity, sex hormones, daytime nap, circadian rhythm, and genetics (Fig.1). The effect of sleep and mood on each other is also addressed. Pictorial models that hypothesise learning on an emotion scale and vice-...
Circadian rhythm disturbances in depression. Hum Psychopharmacol. 2008;23(7):571-585. doi:10.1002/hup.964 PubMedGoogle ScholarCrossref 73. Westen D, Muderrisoglu S, Fowler C, Shedler J, Koren D. Affect regulation and affective experience. J Consult Clin ...
Circadian rhythm dysfunction has been associated with inflammation in the periphery, but the role of the circadian clock genes in neuroinflammation remains poorly understood. Neuroinflammation is widely regarded as inflammation of the central nervous system, which includes microglia activation and increases ...
sleep; gut microbiome; gut microbiota circadian rhythms; nutrition; psychiatric diseases1. Introduction 1.1. Background Sleep is not only necessary for recovery from physical and mental illness, but is also essential for a range of brain functions such as neural cell growth, synaptogenesis and ...