Sleep in humans is under the dual control of circadian rhythmicity and homeostatic process, which is in turn related to the depth of sleep and duration of prior wakefulness. In the normal aging process, profound variations have been found in the daily sleep wake cycles. Rapid Eye Movement (...
Circadian rhythms and sleep are fundamental biological processes integral to human health. Their disruption is associated with detrimental physiological consequences, including cognitive, metabolic, cardiovascular and immunological dysfunctions. Yet many of the molecular underpinnings of sleep regulation in health...
Circadian rhythms and sleepHumans need about seven to nine hours of sleep per night. Sleep habits are heritable, associated with brain function and structure, and intrinsically related to well-being, mental, and physical health. However, the biological basis of the interplay of sleep and health ...
is a multidisciplinary journal for the publication of original research and review articles on basic and translational research into sleep and circadian rhythms. The journal focuses on topics covering the mechanisms of sleep/wake and circadian regulation from molecular to systems level, and on the...
Effects of exercise on circadian rhythms in humans. Front. Pharmacol. 2023, 14, 1282357. [CrossRef] 10. Lou, X.; Wang, H.; Tu, Y.; Tan, W.; Jiang, C.; Sun, J.; Bao, Z. Alterations of sleep quality and circadian rhythm genes expression in elderly thyroid nodule patients and ...
Chronobiologyis the study of physiological cycles and rhythms that occur in living organisms, including humans. The word comes from Greek,chronos, meaning “time,”bio, meaning “life” andologia, meaning “the study of.” Many biological systems occur in patterns or rhythms, such as eating, s...
Sleep/wake timing shifts later in young humans during the second decade of life. In this review we describe sleep/wake patterns, changes in these patterns across adolescence, and evidence for the role of environmental, psychosocial, and biological factors underlying these changes. A two-process mod...
How does circadian rhythm affect sleep? The Biology of Sleep: Humans need sleep in order to survive. The amount of sleep that humans need depend on the age of the individual as well as other circumstances such as health and situational factors. What is indisputable is the fact that the lack...
in mice. These neurons were found to be part of the neural pathway that is crucial for the circadian regulation of sleep and wakefulness. Overactivity of CRF neurons due to stress or disturbed circadian rhythm is likely to cause insomnia and other sleep disorders in humans. Credit: Daisuke ...
Regulation of Sleep and Circadian Rhythms, Vol. 133. Marcel Dekker, Inc.: New York, 1999; 19–80. Google Scholar Cirelli C, Tononi G. Differences in brain gene expression between sleep and waking as revealed by mRNA differential display and cDNA microarray technology.J. Sleep Res.1999;8: ...