Air pollution causes negative impacts on health. Systemic lupus erythematosus (SLE) is an autoimmune disease with diverse clinical manifestations and multifactorial etiology. Recent studies suggest that air pollution can trigger SLE and induce disease ac
Download: Download full-size image Figure 1. [A]: Model of Suffering in Chronic Disease (from Cassell4 [B]: Adaptation of the Model of Suffering in Chronic Disease, From Presented Results This same model can be used to identify possible mechanisms to alleviate chronic suffering. One possibility...
Vollenhoven 1Stanford University, Palo Alto, CA, USA; 2UCB Pharma, SA, Brussels, Belgium; 3Adelphi Real World Ltd, Macclesfield, Cheshire, UK; and 4The Karolinska Institute, Stockholm, Sweden An independent cross-sectional survey assessed systemic lupus erythematosus (SLE) disease and treatment ...
The aim of this study was to assess separately the anti-C1q antibodies and C1q component in the serum from 65 patients with SLE, then in individuals with (n=33) and without (n=32) lupus nephritis and with active (n=36) and nonactive (n=29) form of the disease (European Consensus ...
Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease characterized by circulating autoantibodies and the formation of immune complexes. In these responses, the selecting self-antigens likely derive from the remains of dead and dying cells, as well as from disturbances in clearance. Du...
Morrow, W.J.M. , Isenberg, D.A. , Parry, H.F. , Shkn, L. , Okolie, E.E. , Farzaneh, F. , Shall, S. & Snaith, ML. ( 1982 ) Studies on auto antibodies to poly (adenosine diphosphate ribose) in SLE and other autoimmune disease . Ann. rheum. Dis . 41 , 396 ....
49 women with symptomatic coronary heart disease (CHD) and 279 women without CHD were also analysed. Results: Overall, 21/75 (28%) patients had CAC. Low HDL cholesterol levels <1.40 mmol/l (p=0.03, OR=1.8, 67% v 39%) and cigarette smoking (p=0.01, OR=5.7, 76% v 44%) were ...
Thus, EBM appears to be mandatory in myocarditis with fulminant presentation and when an autoimmune form is suspected for a safe immunosuppression (PCR virus negative myocarditis). In our scenario, the coexistence of an autoimmune disease (SLE) and the detection of a positive serology and PCR DNA...
Systemic lupus erythematosus(SLE) is a chronic sys- temic autoimmune disease. There are different regimens for maintenance therapy of the disease. Corticosteroids play a key role in control of SLE patients' symptoms. As previous studies showed, there is a relationship between steroid use and ...
In those with follow-up data, the mean EMP count decreased from 32 709/ml (SD 7186) to 15 662/ml (SD 5658; p=0.04) and RHI improved (mean RHI 1.75 (SD 0.2) vs 2.72 (SD 1.2; p=0.16) with better disease control. Conclusions Active SLE is associated with higher levels of ...