基因名 Slc33a1 基因曾用名 Acatn; AI315656; AI788741; D630022N01Rik NCBI ID 11416 MGI ID 1332247 Ensembl ID ENSMUSG00000027822 Pubmed Slc33a1 人类同源基因 SLC33A1 品系描述 These strains carry loxP sites flanking exon 2 of Slc33a1 gene. When crossed with a Cre recombinase-expressing strain,...
Keap1ing an eye on Slc33A1KEAP1 is a tumor suppressor encoded by a gene commonly mutated in lung cancer. A systematic search for Keap1-mutant cancer vulnerabilities now reveals that Slc33a1 is a context-specific essential gene that represents a promising new anti-cancer target....
20Abstract:ToinvestigatethemechanismofhumanSLC33A1gene mutationcausinghereditary spasticparaplegiaHSP,wegeneratedamousemodelwithslc33a1S113R mutation.When heterozygousmicewerecrossedtowildtypemice,heterozygoteswere recoveredataratio expectedofMendelianinheritance.However,whenheterozygousmice ...
Entrez Gene ID:(Human) 9197 功能 acetyl-CoA transporter activitysolute:proton symporter activitysecondary carrier transporter 参与通路 transportacetyl-CoA transportproton transportBMP signaling pathwaytransmembrane transportSMAD protein signal transduction
KEAP1 is a tumor suppressor encoded by a gene commonly mutated in lung cancer. A systematic search for Keap1-mutant cancer vulnerabilities now reveals that Slc33a1 is a context-specific essential gene that represents a promising new anti-cancer target.
Entrez Gene ID:(Human) 9197 功能 acetyl-CoA transporter activitysolute:proton symporter activitysecondary carrier transporter 参与通路 transportacetyl-CoA transportproton transportBMP signaling pathwaytransmembrane transportSMAD protein signal transduction
Exon 2 of Slc33a1 gene was deleted to generate Slc33a1 knockout mice. *使用本品系发表的文献需注明: Slc33a1-KO mice (Cat. NO. NM-KO-201902) were purchased from Shanghai Model Organisms Center, Inc.. 相关品系 Slc33a1-Flox 品系名:C57BL/6Smoc-Slc33a1em1(flox)Smoc 品系状态:精子冻存...
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Figure 3. Genomic Structure and Localization of the Mutations in the SLC33A1 Gene The coding region is depicted in gray. Missense mutation, arrow; nonsense mutation, X; splice site mutation, asterisk; insertion, down triangle; deletion, up triangle. To assess the functional consequences of the ...