so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG). [provided by RefSeq, Ma...
这种转运蛋白是回肠远端顶端细胞摄取肠道胆汁酸的主要机制胆汁酸是胆固醇代谢的分解代谢产物,因此这种蛋白质对胆固醇的稳态也至关重要。该基因突变可引起原发性胆汁酸吸收不良(pbam);该基因突变还可能与其他肝肠疾病有关,如家族性高甘油三酯血症(fhtg)。[由RefSeq提供,2010年3月]This gene encodes a sodium/bile ...
This invention relates to polymorphisms in the human SLC10A2 gene and corresponding novel allelic polypeptides encoded thereby. The invention also relates to methods and materials for analysing allelic variation in the SLC10A2 gene, and to the use of SLC10A2 polymorphism in treatment of diseases ...
caspase 7, PTEN, P21, P53, LKB1, TSC2 were increased and the expression of Bcl-2, cyclin D1, c-FLIP were declined in NSCLC cells and slc10a2 overexpressed NSCLC cells with the treatment of bexarotene, and the opposite situations were seen after slc10a2 gene was silenced in NSCLC cells...
Gene Symbol Slc10a2* NCBI Accession NP_035518.1 Concentration 0.5 mg/ml Buffer Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Availability Shipped within 1-3 working days. Note This product is for research use only. 产品留言 标题 联系...
The transcription and protein levels of the SLC10A2 gene were both significantly down-regulated in the choledocholithiasis with chorionic villi (P<0.05). Conclusion Our study suggests that chorionic villi formation in cholecystectomy is closely related to genesis of choledocholithiasis after...
A. (2002) Human apical sodium-dependent bile salt transporter gene (SLC10A2) is regulated by the peroxisome proliferator-activated receptor α. J. Biol. Chem. 277, 30559-30566Jung D, Fried M, Kullak-Ublick G. Human apical sodium-dependent bile salt transporter gene (SLC10A2) is regulated...
The invention also relates to methods and materials for analysing allelic variation in the SLC10A2 gene, and to the use of SLC10A2 polymorphism in treatment of diseases with SLC10A2 drugs.doi:WO2002083944 A2JOHN EDWARD NORRIS MORTENWO
This invention relates to polymorphisms in the human SLC10A2 gene and corresponding novel allelic polypeptides encoded thereby. The invention also relates to methods and materials for analysing allelic variation in the SLC10A2 gene, and to the use of SLC10A2 polymorphism in treatment of diseases ...
A.Human ileal bile acid transporter gene ASBT (SLC10A2) is transactivated by the glucocorticoid receptor. Gut . 2004Jung D, Fantin AC, Scheurer U, Fried M, Kullak-Ublick GA. Human ileal bile acid transporter gene ASBT (SLC10A2) is transactivated by the glucocorticoid receptor. Gut 2004;...