U-104 (SLC-0111) 是一种有效的CAIX 和CA XII碳酸酐酶 (CA) 抑制剂,Ki值分别为 45.1 nM 和 4.5 nM。U-104 在小鼠模型中显示出明显的肿瘤生长延迟。 MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务 U-104Chemical Structure ...
The amide form is found to be the only stable tautomeric form in both the phases, with the trans-cis conformer as the most stable structure in the gas phase and the trans-trans conformer in aqueous solution. The deprotonation of the sulfonamide nitrogen leading to the formation of the SLC-...
U-104(Synonyms: SLC-0111)纯度: 99.91% U-104 (SLC-0111) 是一种有效的 CA IX 和 CA XII 碳酸酐酶 (CA) 抑制剂,Ki值分别为 45.1 nM 和 4.5 nM。U-104 在小鼠模型中显示出明显的肿瘤生长延迟。 U-104Chemical Structure CAS No. :178606-66-1 *Please selectQuantitybefore adding items. 生物活性 ...
Structure activity relationship for this class of sulfonamides is discussed in detail.doi:10.1016/j.bmc.2017.03.027Carta, FabrizioVullo, DanielaOsman, Sameh M.AlOthman, ZeidSupuran, Claudiu T.Bioorganic & Medicinal ChemistryCarta F, Vullo D, Osman SM, et al. Synthesis and carbonic anhydrase ...
RESULTS AND CONCLUSION: (1) The FC-S composite nanoplatform was successfully prepared with a well-defined rhombic dodecahedral structure, uniform size and good dispersion. Its particle size was about 323 nm; zeta potential was about -11.1 mV, and the nanoplatform had a certain ...
IR (infrared), NMR (nuclear magnetic resonance) spectroscopy and EA (elemental analysis) were used in the characterization of the structure. In order to explore the potentiality of our newly synthesized product to inhibit Cas, a docking simulation was performed on the binding pockets of both ...