As the body’s integumentary system, the skin is vulnerable to injuries. The subsequent wound healing processes aim to restore dermal and epidermal integrity and functionality. To this end, multiple tissue-resident cells and recruited immune cells cooper
Wound healing and skin regeneration. Cold Spring Harb Perspect Med. 2015;5(1):a023267-a023267. doi: 10.1101/cshperspect.a023267M. D. Leonida and I. Kumar, "Wound healing and skin regen- eration," in Bionanomaterials for Skin Regeneration, pp. 17-25, Springer, 2016....
While typically involved in hair regeneration, HFSC may also differentiate into epithelial cells, promoting skin repair [137]. By facilitating the restoration of the cutaneous barrier, HFSC then contributes to the prevention of wound infection and water loss. As mentioned above, Tregs are able to m...
The biocomposite material is made from silk fibroin, sodium alginate and other natural polymers. When applied to a wound, its micro-nano layered structure guides skin cells to "climb" to various skin layers, promoting full-thickness skin repair and regeneration, according to Wang Xinyu, a profess...
Of course, they cannot be used in skin substitute development as a cell component; but they can provide bioactive substances, which can improve the wound healing process [40]. Table 1 Somatic and stem cells used in skin tissue regeneration Full size table Fibroblasts and keratinocytes are common...
Therefore, there is a need of new strategies to promote wound healing and tissue repair. When talking of wound healing, a distinction is made between regeneration and repair. Regeneration is used to refer to the complete replacement of damaged tissue with new tissue not associated with scar tissu...
This chapter discusses injuries related to the skin and wound healing. The process of healing of a skin wound in mammals is a combination of epidermal regeneration and wound contraction. Epidermal continuity is re-established initially by a process of sliding out of the cells at the periphery of...
A research paper published in Science Translational Medicine presents a significant breakthrough in the area of skin regeneration and wound healing by researchers at the Wake Forest Institute for Regenerative Medicine (WFIRM).
Polymeric hydrogels for burn wound care: Advanced skin wound dressings and regenerative templates skin regenerationwound healingwound dressingWound closure represents a primary goal in the treatment of very deep and/or large wounds, for which the ... M Marta,D Christian,S Alessandro,... - 《Burns...
Emerging skin regeneration techniques involving scaffolds activated with growth factors, bioactive molecules and genetically modified cells are exploited to overcome wound healing technology limitations and to implement personalized therapy design. 展开