- deep tissue infection - pain out of proportion - dishwater discharge - rare: la belle indifference - polymicrobial: strep pyogenes, MRSA - tx: broad spectrum abx (+clindamycin) - surgical emergency necrotizing fasciitis case: pt presents w/ small pimple that hurts like hell ...
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, 2006) and, despite the sterile nature of the pustules, secondary bacterial infection with Staphylococcus aureus may supervene. Hence, an immature skin barrier, combined with a reduced contribution of EGFR-driven innate immune mechanisms of the epidermis, could contribute to this adverse skin ...
-inflammatory cytokines such asIl-10. KEGG (Kyoto Encyclopedia of Genes and Genomes) pathway analysis corroborated enriched GO terms and identified significant enrichment of the pathways “complement and coagulation cascades” (ko04610), “Staphylococcus aureusinfection” (ko05150), “cytokine-cytokine re...
If the infection is not controlled in a timely fashion, a biofilm can form. Biofilm formation results in the secretion of an exopolysaccharide matrix, which can protect bacteria from antibiotic treatment and host immune response. In the presence of bacteria and endotoxins, the level of inflammatory...