Agent Orange, or 2,3,7,8-tetrachlorodibenzodioxin, has been shown to cause indirect DNA damage, producing malignancies. However, its connection to nonmelanotic invasive skin cancer is unclear. This study investigated whether 2,3,7,8-tetrachlorodibenzodioxin exposure increases the incidence of this ...
2008). Since then, applications of nanoemulsions for probable treatments of different types of cancer by a variety of drugs have been investigated extensively. Nanoemulsion systems have been also studied for transdermal delivery of caffeine as a skin-protecting agent against sun exposure (Shakeel and ...
Skin cancer is the most common form of cancer, affecting over 3.5 million people in the United States alone. The incidence of skin cancer is steadily increasing in frequency each year; although enhanced leisure time exposure to sunlight has been proposed as a cause, another factor may be an ...
Due to today’s high sensitivity of DNA analysis, only a few skin cells are required for DNA analysis. Even then, of the few potentially present cells, it may be rare to find ones that are still available for nuclear DNA analysis; shed cells are mainly from the outer layers of the ...
Lightweight emollient that is derived from olives (or in some cases wheat germ or rice bran). Hydrogenation of olive-derived squalane gives it stability and enables its use in skin care. Luxurious, non-comedogenic oil that the skin readily absorbs due to its similarity to the skin’s own se...
Stanford University, California; and 10Geisinger Health System, Geisinger Cancer Institute, Danville, Pennsylvania A panel of national experts was convened by the Infectious Diseases Society of America (IDSA) to update the 2005 guidelines for the treatment of skin and soft tis...
For the third consecutive decade, skin cancer is on the rise with the highest mortality rates amongst those with darker skin tones. Even though the summer season is over, we are still at risk. A surprising 80% of sun damage comes from everyday exposure[1]. Consequently, there is still a...
Considering that skin photoaging is characterized by increased epidermal thickness and tissue atrophy due to collagen degradation [28], H&E staining was performed in the dorsal skin sections for histological analysis. UVB exposure increased epidermal thickness, destruction of the keratin layers, and infi...
These functions are detrimentally affected by, for example, dryness, yeast, and structural changes in the skin, such as due to aging and excessive sun exposure. Various pharmaceuticals have been used for the treatment or prevention of skin conditions, including skin cleansing compositions. Some ...
due to their interaction with nucleic acid, proteins and lipids. Reactive oxygen species oxidize (take electrons from) ascorbate first to monodehydroascorbate and then dehydroascorbate. The reactive oxygen species are reduced to water while the oxidized forms of ascorbate are relatively stable and un...