In developed countries, interest in cutaneous aging is in large part the result of a progressive, dramatic rise over the past century in the absolute number and the proportion of the population who are elderly (Smith et al, 2001). The psychosocial as well as physiologic effects of skin aging...
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The interaction between skin aging and melanoma derives from the contributions of chronologic aging and photoaging and the subsequent changes that occur in each scenario in the skin. The resultant changes in skin dynamics and their impact on melanoma development and progression are the focus of this ...
1and expected that skin aging also correlates with the state of local stem cells pools in the skin. Recently, a skin-specific p53 activation mouse model, generated by conditionally deleting Mdm2, showed gradual thinning of the epidermis and loss of hair follicle...
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Advanced Glycation End products (AGEs) and sends the measurement result to the SkinAge app through Bluetooth. The SkinAge app translates this into an easy to understand SkinAge result that compares your calendar age with the aging of your skin. Measurement results can be saved and shared ...
In conclusion, fibroblasts isolated from intrinsically aged skin exhibit some, but not all, molecular hallmarks of cellular senescence. Most importantly, they secrete a unique pattern of proteins that is distinct from the canonical SASP and might reflect specific processes of skin aging....
skin aging is still largely insufficient. Despite the fact that skin aging is readily visible and morphologically well defined, the underlying molecular mechanisms driving that process are still a matter of debate as is the role of stem cells therein. Furthermore, the aging of skin is peculiar ...
Effect of Botanicals on Inflammation and Skin Aging: Analyzing the Evidence,Brain-Skin Connection: Stress, Inflammation and Skin Aging,Neuromodulatory and Anti-Inflammatory Ingredient for Sensitive Skin: In Vitro Assessment,Biological Treatments... P Doi - Inflammation & Allergy - Drug Targets 被引量...
Understanding human skin aging requires in-depth knowledge of the molecular and functional properties of various skin cell types. We performed single-cell RNA sequencing of human eyelid skin from healthy individuals across different ages and identified eleven canonical cell types, as well as six ...