Which X chromosome is silenced is selected at random, and so it is expected that each X chromosome will be silenced in 50% of cells. However, as individuals age and develop new immune blood cells, some develop a pattern of X chromosome inactivation—skewed X chromosome inactivation—that ...
Oliviero B, Mantovani S, Ludovisi S, Varchetta S, Mele D, Paolucci S, Baldanti F and Mondelli MU: Skewed B cells in chronic hepatitis C virus infection maintain their ability to respond to virus‑induced activation. J Viral Hepat 22: 391‑398, 2015....
Skewed T-Cell Receptor Usage and Junctional Heterogeneity Among Isletitis and T-cells in Human IDDM Santamaria, P., Lewis, C., Jessurun, J., Sutherland, D. E. and Barbosa, J. J. 1994. Skewed T-cell receptor usage and junctional heterogeneity among isletitis ab and cd T-cells in hum...
T cells in cardiac allograft vasculopathy are skewed to memory Th-1 cells in the presence of a distinct Th-2 population. Am J Transplant. 2008; 8 :1040–1050.Hagemeijer MC, van Oosterhout MF, van Wichen DF, van Kuik J, Siera-de Koning E, Gmelig Meyling FH, et al. T cells in ...
Skewed X chromosome inactivation (XCI) is a rare reason for hemophilia B in females. It is indefinite whether X chromosome reactivation (XCR) would occur when cells of hemophilia B patients with skewed XCI were reprogrammed into induced pluripotent stem cells (iPSCs). In this study, we invest...
A positive-feedback loop between tumour infiltrating activated Treg cells and type 2-skewed macrophages is essential for progression of laryngeal squamous cell carcinoma Wei Sun, Fan-Qin Wei, Wei-Jin Li, Jia-Wei Wei, Hua Zhong, Yi-Hui Wen, Wen-Bin Lei, Lin Chen, Hang Li, ...
S. Korematsu, Y. Tanaka, T. Nagakura, N. Minato, and T. Izumi, "Human 𝛾𝛿 T cells modulate the mite allergen-specific T-helper type 2-skewed immunity," Clinical and Experimental Allergy, vol. 37, no. 11, pp. 1681-1687, 2007....
CD8(+) T cells play important roles in anti-tumor immunity but distribution profile or functional characteristics of effector memory subsets during tumor progression are unclear. We found that, in oral squamous carcinoma patients, circulating CD8(+) T cell pools skewed toward effector memory subsets...
SkewedDistributionofIL-7Receptor-a-Expressing EffectorMemoryCD8 + TCellswithDistinctFunctional CharacteristicsinOralSquamousCellCarcinoma Jang-JaerLee 1. ,Chiou-YuehYeh 2. ,Chiau-JingJung 2 ,Ching-WenChen 2 ,Mao-KuangDu 2 ,Hui-MingYu 3 , Chia-JuYang 2 ,Hui-yiLin 4 ,AndySun 1 ,Jenq-YuhKo 5...
Skewed immunological balance between Th17 (CD4(+)IL17A (+)) and Treg (CD4 (+)CD25 (+)FOXP3 (+)) cells in human oral squamous cell carcinoma. Skewed immunological balance between Th17 (CD4(+)IL17A (+)) and Treg (CD4 (+)CD25 (+)FOXP3 (+)) cells in human oral squamous cell ...