Skeletal muscle makes up 40% of our body mass, is essential for movement and has pivotal roles in metabolism and immune regulation1,2,3. The major components of skeletal muscle, the multinucleated myofibers (MFs), are classified into ‘slow-twitch’ (type I) and ‘fast-twitch’ (type IIA...
The rate of accrual of muscle mass in neonates has not been assessed. We describe the D3-creatine (D3Cr) dilution method, a noninvasive assessment of muscle mass in neonates. A total of 76 neonates >26-week-old corrected gestational age were enrolled
As in disease states, muscle strength is one of the best predictors of longevity with aging [12]. Therefore, the maintenance of skeletal muscle mass is essential for improving longevity as well as the quality of life. Extensive research over the past 15 years has improved our understanding of...
Skeletal muscle mass to visceral fat area ratio is associated with metabolic syndrome and arterial stiffness: the Korean Sarcopenic Obesity Study (KSOS) Diabetes Res Clin Pract. 2011; 93 (2):285–291. doi: 10.1016/j.diabres.2011.06.013. [ Cross Ref ]...
Thus, the protection observed in the 1-month-old tongue of the mdx muscle, close to the 20th day degeneration peak, may be related to the high levels of glycine presented in our study. In mdx and control mice, a gradual decline in muscle mass becomes apparent around 18 months, marking ...
Skeletal muscle undergoes atrophy and loss of force during long space missions, when astronauts are persistently exposed to altered gravity and increased ionizing radiation. We previously carried out mass spectrometry-based proteomics from skeletal muscl
When skeletal muscle is damaged, it is repaired by the proliferation of mononuclear muscle precursor cells (mpc) which fuse either with one another to form young multinucleated muscle cells (myotubes) or with the ends of damaged myofibres (Robertson et al., 1990). The success of new muscle ...
Cardiac cachexia is defined as a complex syndrome characterized by involuntary weight loss in advanced heart failure due to reduced fat, bone, and skeletal muscle mass4,5,6. Skeletal muscle wasting, which occurs in up to 20% of CHF patients, can develop prior to full cachexia and might ...
5.-312-328 (1971) cell size developmental physiology DNA growth retardation muscle mass protein malnutrition Review Article Skeletal Muscle Cell Mass and Growth: The Concept of the Deoxyribonucleic Acid Unit DONALD B. CHEEK'1451, ALAN B. HOLT, DONALD E. HILL, AND JAMES L. TALBERT Division of...
Again, pro-hypertrophic NOX2-NOX4 cooperation may occur since NOX4 was reported to be required for skeletal muscle hypertrophy in response to synergist ablation [55]. The lack of training-induced hypertrophy could be connected to the impaired glucose metabolism, since, in humans, muscle mass ...