in heart failure patients, we hypothesized that skeletal muscle as one of the largest tissues of the body might play a pivotal role in preventing the progression of CHF by producing cardioprotective myokines. While it is known that the heart secretes factors under pathological conditions to trigger...
Microscopic images with appropriate staining techniques are proven to be highly reliable in studying the histology of human body, with different image segmentation techniques are applied on these types of images and provide an encouraging outcome to further analyze the composition of the human tissues....
Scale bar of image with FDB muscle = 500 μm. Scale bar of microscopic fluorescent images = 50 μm. The relationship between pericyte subtypes is unknown. They may represent developmental stages of the same cell. Future studies will use a Cre/loxp system such as NG2–CreER or/and Nestin...
The following papers by Richard Lieber (Skeletal Muscle as an Actuator), Thomas Roberts (Elastic Mechanisms and Muscle Function), Silvia Blemker (Skeletal Muscle has a Mind of its Own: a Computational Framework to Model the Complex Process of Muscle Adap
brain. In the first ascending pathway, the somatosensory neurons in dorsal root ganglia (DRG) project to the brain via the spinal dorsal horn (SDH). This pathway primarily conveys somatic sensations such as temperature, injury, and pain-related signals from the skin, muscle, and skeleton.21,...
The regions of each bone where muscles attach to the bone grow larger and stronger to support the additional force of the muscle. In addition, the overall mass and thickness of a bone increase when it is under a lot of stress from lifting weights or supporting body weight. Hematopoiesis Red...
Typical two-dimensional (2D) culture models of skeletal muscle-derived cells cannot fully recapitulate the organization and function of living muscle tissues, restricting their usefulness in in-depth physiological studies. The development of functional 3D culture models offers a major opportunity to mimic...
The onset of rigor mortis will be rapid if the muscle is kept at low pH and high temperature, while rigor will be delayed if abundant muscular glycogen stores at the time of death and will be weak if the animal was debilitated at the time of death. Microscopic Evaluation. Histologic ...
Carpenter S: Light-microscopic pathology of skeletal muscle. Ch. 7 in Disorders of Voli~ntaryMuscle, 6th ed, Walton JN, Karpati G (eds). Churchill-L~vingstone,Edin- burgh, 1994, pp 233-259Carpenter S. Light-microscopic pathology of skeletal muscle. In: Walton J, Karpati G, Hilton-...
FIGS. 2A-B demonstrate that Myf5, Myod and Mrf4 are master regulators of skeletal muscle and are restricted to skeletal muscle in development and in the adult. Shown here is Myod-GFP transgenic expression which is restricted to the somites, diaphragm and established skeletal muscle in mouse at ...