The large number of tumor markers (>50) and putative drug targets (>100) exposed a vast potential for yet unexplored detection and targeting opportunities, whereas the presence of 15 antigen immunological markers enabled an assessment of epithelial, mesenchymal or stemness characteristics. Serum-...
The characteristics of each cell line used are displayed in Supplementary Table S1. The combination of agents induces apoptosis in breast cancer cells The selected agent concentrations were based on the calculated CI index as shown in Table 1. An additional consideration was to select YM155 ...
Table 1.The primer sequences and amplified characteristics. Transcripts of VEGF-A, Quek1 (quail receptor for VEGF-A), interleukin 8, TLR-7, interferon α, and GAPDH (glyceraldehyde-3-phosphate dehydrogenase) were analyzed using LightCycler®Nano (Roche). Final data were normalized to GAPDH mRN...
Table 1. Clinico-pathological characteristics of the study patients. 2.10. Immunohistochemistry Assay After surgical excision, the tissue sample was stored in 10% neutral buffered formalin for fixation and subsequent insertion in the paraffin block. Tumors that were formalin-fixed and paraffin-embedded...
breast cancer cell linetumor cellscultured/substance effectsculture mediagene expression profilingBackground and objectives: Cell culture is one of the mainstays in the research of breast cancer biology, although the extent to which this approach allows to preserve the original characteristics of ...