Kevin Wyndham, Waters Senior Director, R&D Chemistry Technologies Center, provides a brief background on Size-Exclusion Chromatography (SEC) and Water’s role in SEC’s development.This is a modal window. This video is either unavailable or not supported in this browser ...
NANOSCALE -CAMBRIDGE-KothalawalaN.LeeWestIVJ.DassA.Kothalawala, N.; Lee West, J., IV; Dass, A. Size-dependent molecule-like to plasmonic transition in water-soluble glutathione stabilized gold nanomolecules. Nanoscale 2014, 6, 683-687....
respective fractions in the formulations, to determine the absolute size distribution profiles of the LPX nanoparticles formulations, and to derive important size-related parameters such as the size-dependent structure and composition of the particles including the quantification of mRNA molecule per LPX....
Water, ions and small biomolecules, up to ~5 nm in diameter, can pass through an NPC largely unimpeded. Unassisted transport of larger molecules is blocked6,7,8, but, when combined with nuclear transport factors, cargoes up to 40 nm in diameter can traverse an NPC9,10, fueled by a...
Nanoliposomes are vesicles with an average particle size of around 20 to 150 nm, composed of phospholipids that can entrap hydrophobic and hydrophilic drugs in their structure. Many natural constituents, such as soybean lecithin (SBL), egg yolk, sunflower, etc., can be used to nanofabricate ...
where R is the gas molecule constant, T is the thermodynamic temperature; M is the molecular mass of the gas (in moles). At the steady temperature, υ¯ can be a constant for the same kind of gases. In addition, the geometrical factor of the porous body can be expressed as (9-42...
Oral administration has always been considered one of the best administration routes, however some poorly soluble small molecule drugs and macromolecular proteins, peptides, and nucleic acid drugs can be limited by degradation or being difficult to absorb in the gastrointestinal tract, making their oral...
wt of 22600 and a diam. about 10 nm, which compared quite well with data obtained from ultracentrifugation, light scattering and viscosity measurements. Polymer sizes were in agreement with molecular weight determinations from ultracentrifugation and light scattering, assuming that the volume and weight...
Related resources Application Note Instrument adaptability and reliability, together with regulatory compliance and ease of method transfer between instruments, are all key factors to ... Small-molecule drug substances: Regulation-compliant, reliable particle sizing using the Mastersizer 3000+ ...
Plasmonic nanoparticles are widely used in multiple scientific and industrial applications. Although many synthesis methods have been reported in the literature throughout the last decade, controlling the size and shape of large populations still remains as a challenge. As size and shape variations have...