Furthermore, in contrast to alternative methods, iSCAT enables quantitative molecular weight (MW) measurements of biomolecules, since the signal intensity is proportional to the weight of the imaged object12,16. However, and as a key point, these three label-free optical single-molecule detection ...
Hodgkiss, Small molecule detection in solution via the size contraction response of aptamer functionalized nanoparticles, Biosens. Bioelectron. 57 (2014) 262-268.Alsager, O.A., et al., Small molecule detection in solution via the size contraction response of aptamer functionalized nanoparticles. ...
where R is the gas molecule constant, T is the thermodynamic temperature; M is the molecular mass of the gas (in moles). At the steady temperature, υ¯ can be a constant for the same kind of gases. In addition, the geometrical factor of the porous body can be expressed as (9-42...
Water, ions and small biomolecules, up to ~5 nm in diameter, can pass through an NPC largely unimpeded. Unassisted transport of larger molecules is blocked6,7,8, but, when combined with nuclear transport factors, cargoes up to 40 nm in diameter can traverse an NPC9,10, fueled by a...
The adsorption mechanism of EDTA on the surfaces of nanoparticles was researched by a Fourier transform infrared spectroscopy. It was speculated that EDTA adsorbed on the surfaces of nanoparticles by the dehydration reaction of carboxyl groups in the molecule of EDTA and hydroxyl groups on surfaces ...
Two other factors were found to have an influence on retention of organic molecules: the polarity of the molecule, and the charge of the molecule. The importance of these factors depends on the molecules as well as on the type of membrane. 展开 关键词: Nanofiltration Molecular size Polarity ...
Related resources Application Note Instrument adaptability and reliability, together with regulatory compliance and ease of method transfer between instruments, are all key factors to ... Small-molecule drug substances: Regulation-compliant, reliable particle sizing using the Mastersizer 3000+ ...
1). The z-dimension was chosen sufficient to prevent interaction of the LCC molecule with two surfaces at the same time. This lead to simulation box sizes \(6.76 \times 6.23 \times 10.91\) nm\(^3\), \(6.52 \times 7.27 \times 10.00\) nm\(^3\), and \(8.52 \times 8.30 \times ...
The Hydrogen Bond and the Water Molecule. (Elsevier B. V., 2007). 38. Dusek, U. et al. Size matters more than chemistry for cloud-nucleating ability of aerosol particles. Science 312, 1375–1378 (2006). 39. Sorjamaa, R. & Laaksonen, A. The effect of Atmos. Chem. Phys. 7, ...
respective fractions in the formulations, to determine the absolute size distribution profiles of the LPX nanoparticles formulations, and to derive important size-related parameters such as the size-dependent structure and composition of the particles including the quantification of mRNA molecule per LPX....