Primary role for endoplasmic reticulum-bound ribosomes in cellular translation identified by ribosome profiling In eukaryotic cells, the spatial regulation of pro Reid,W D.,Nicchitta,... - 《Journal of Biological Chemistry》 被引量: 167发表: 2012年 The mode of action of restrictocin and mitogil...
Answer to: Prokaryotic and eukaryotic ribosomes have the same size and shape and are both involved in the process of translation. A) True B) False...
True or False: PAMPs are present on specific phagocytic cells and recognize PRRs on the surfaces of other cells in the host. Glycolipid anchored proteins are made exclusively by free ribosomes and are found exclusively attached to the intracellular sur...
A well-studied circumstance under which cells depart from their typical size range but lose normal cellular function is cellular senescence. This was first observed in the 1960s in seminal work by Hayflick and Moorhead, who identified a permanent state of cell cycle arrest in serially cultivated ...
The association of ribosomes with ER membranes could play a role in ensuring this proportionality, given that ribosome number generally scales with overall cell size23. Barrier proteins such as Lem2 and Lnp1 could act like valves regulating membrane flow through the cellular membrane network, such...
Most organs scale proportionally with body size through regulation of individual cell size and/or cell number. Here we addressed how postmitotic and morphologically complex cells such as neurons scale with the body size by using the dendritic arbor of on
[57]. Since the number of ribosomes is indicative of cell size, protein synthesis rate will correlate with cell size. Therefore, only once a certain cell size is reached will there be sufficient Cln3 to drive the transition through start. This is thought to involve the activation of the ...
To test whether importin β1 also might be locally translated in the axons of actively growing neurons, we took advantage of the RiboTag transgenic mouse model (Sanz et al., 2009) to examine endogenous mRNA interaction with ribosomes. We crossed RiboTag and Islet1-Cre mice to generate HA-...
As an animal's body size increases, the number of cells in the organism also increases. Why must the number of cells increase in order to increase body size? Why can't there simply be the same number of cells, each wit...
Answer to: In what two ways do eukaryotic cells overcome some of the limitations on cell size to allow them to be larger than prokaryotic cells? By...