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We use this high-resolution spatial map to characterize fundamental steps in the patterning of the midbrain–hindbrain boundary (MHB) and the developing gut tube. We uncover axes of cell differentiation that are not apparent from single-cell RNA-sequencing (scRNA-seq) data, such as early dorsal...
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function are unknown. When we compared DEGs for these perturbations, they form two major groups in accordance with known genetic interactions20,21,22. Moreover, the DEGs are enriched for biological processes and pathways involved in brain and nervous system development, offering new hypotheses for ...
single-stock ETF offers 1.25x leverage on the tech company. Unsurprisingly, these shares have crashed year to date and demonstrate the risky nature of holding onto single-stock ETFs over the long run. However, shares gained 3.5% in the first week of August. The ETF's expense rati...
function are unknown. When we compared DEGs for these perturbations, they form two major groups in accordance with known genetic interactions20,21,22. Moreover, the DEGs are enriched for biological processes and pathways involved in brain and nervous system development, offering new hypotheses for ...
If you're not in a rush, there are certain times of the year that are best for buying a computer. January can be a prime time to snag a bargain on a computer. Other times to buy include holiday weekends and back-to-school season. Over the last 70 or so years, a growing number ...
S1a, b). The complete tissue dataset was grouped into 106 clusters and over 581 cell-type subclusters in the hierarchy (Fig. 1b, c and Fig. S1c). The numbers of cells and unique molecular identifiers (UMIs) per cell detected for each tissue are shown in Fig. 1d and Fig. S1b. ...
Ovarian aging leads to diminished fertility, dysregulated endocrine signaling and increased chronic disease burden. These effects begin to emerge long before follicular exhaustion. Female humans experience a sharp decline in fertility around 35 years