While partial volume correction (PVC) methods have been previously studied, these methods have traditionally been limited by scan time and necessary anatomic information. Magnetic Resonance Imaging (MRI), particularly enabled by simultaneous PET/MR, can serve as a high spatial resolution anatomical ...
Whole-body planar and SPECT/CT imaging at serial time points were performed to determine the volume of 186RNL distributed in the brain and in the tumor, percentage of tumor volume treated (TVT), radiation absorbed dose to the tumor, and whole body normal organ doses. ...
Genome-wide association studies (GWAS) provide a powerful method for identifying the loci and genes that contribute to disease. However, in many cases, the specific cell types and states that confer disease risk through these genes remain unknown. Determ
Notably, DLL3 itself is a potential therapeutic target, which is currently investigated in several preclinical and clinical studies [16, 70]. So far, only a limited number of studies investigated and confirmed the detection of DLL3 expression in CTCs of CRPC and small cell lung cancer patients...
Once the final target of 100 scanning sessions was reached, the final revised stopping criterion was to obtain 48 blood draws (since the RNA-sequencing was performed in batches of six samples), yielding a total of 104 scanning sessions. No time-series statistical analyses were performed before ...
The initial sample target was to collect data for one calendar year, yielding roughly 100 samples. However, due to travel and the extended hiatus mentioned above, scanning was extended to obtain sufficient samples. Once the final target of 100 scanning sessions was reached, the final revised stop...
type of benefit or objective function used to measure similarity of the chromatographic pair, which is used subsequently to derive retention time correction function (e.g. sum of the squared ion intensity distance of raw data, correlation of raw ion intensity or sum of overlapping peak volume)....
Target- site resistance (knockdown resistance (kdr)) can be easily monitored by PCR, while metabolic resistance is not easily tracked due to its complex molecular basis, despite its greater operational impact on malaria control [1]. The de- tailed molecular and structural basis through which ...
The present invention provides an improved capacitive bead sensor for detection and/or quantification of target analytes in a sample, with a detection limit down to single-beads, wh
The targeting moiety may be any molecule or construct effective to selectively target cells of interest. The SWNT construct may comprise an enzymatic nanofactory and be assembled sequentially in situ at or near a site of interest, e.g., a tumor. Nanofactories are suitable to activate prodrugs ...