calc(minuim_index) single_source_shortest_path() print dist[4]
To address these issues we developed a statistical method, LinTIMaT, which reconstructs cell lineages using a maximum-likelihood framework by integrating mutation and expression data. Our analysis shows that expression data helps resolve the ambiguities arising in when lineages are inferred based on ...
The purpose of this chapter is to provide a comprehensive review of the field of genome rearrangement, i.e., comparative genomics, based on the representation of genomes as ordered sequences of signed genes. We specifically focus on the “hard part” of genome rearrangement, how to handle dupl...
Single-cell RNA sequencing has been instrumental in uncovering cellular spatiotemporal context. This task is challenging as cells simultaneously encode multiple, potentially cross-interfering, biological signals. Here we propose scPrisma, a spectral computational method that uses topological priors to decoupl...
On this account, Dijkstra’s algorithm, which is one of the most efficient algorithms to find the shortest path between the source node and every other node of a graph, is used in this study. The worst case implementation of this algorithm runs in O(|E|+|V|log|V|) (|E|: number ...
cells in the remaining four data sets. For example, we first train the models on Baron and then test them on Segerstolpe, Muraro, Xin, and Wang. Next, we train the models on Segerstolpe and test on the rest, etc. The accuracy of each method is shown in Fig.2and Supplementary Table...
Inferring cell-signaling networks from high-throughput data is a challenging problem in systems biology. Recent advances in cytometric technology enable us to measure the abundance of a large number of proteins at the single-cell level across time. Tradi
Firstly, since the MAC and physical layer include the source ID field, the routing layer packets of node n do not need to include the ID field for each (n,x) edge; thus, duplicate transmissions of ID fields are prevented. Secondly, if an edge-coloring-based MAC layer is used, then ...