A investigation of the formalism connecting the single particle and the many-body level densities is performed from the partition function standpoint. Some applications, based on the saddlepoint method for the evaluation of the integrals. are given as an illustration....
Our approach is based on particle-templated emulsification, which allows single-cell encapsulation and barcoding of cDNA in uniform droplet emulsions with only a vortexer. Particle-templated instant partition sequencing (PIP-seq) accommodates a wide range of emulsification formats, including microwell pla...
It has proved non-trivial to directly measure or theoretically predict the thermal response of irradiated nanoparticles, this is mainly because the light intensity and other physical parameters at the position of the nanoparticle are not known and the particle might disintegrate or change shape38 upon...
Spatially continuous pixels above this threshold were considered a single particle. A two-dimensional Gaussian function was used to determine the centroid of each particle to subpixel precision. Particles within three pixels of consecutive frames were assumed to represent the same PIEZO1-tdTomato ...
E. Optimal point spread function design for 3D imaging. Phys. Rev. Lett. https://doi.org/10.1103/PhysRevLett.113.133902 (2014). Article Google Scholar Ram, S., Prabhat, P., Ward, E. S. & Ober, R. J. Improved single particle localization accuracy with dual objective multifocal plane ...
Green's function reaction diffusion (GFRD) [4,23]. The GFRD algorithm [4,23] and earlier approaches [24,25] use the Green's function (GF) solution to the PDE for a pair of particles diffusing with a reactive boundary between them to propagate particle positions and evaluate reaction ...
we calculated the overlap odds ratio as a function of the number of mice sharing SNVs. Using the mouse strains data as a plausible pool of inherited SNVs, we observed stronger overlap when thresholding the SNVs by higher number of mice that share the SNV (Fig.2C) as seen by the bars...
is the position at timetof a virtual particle with initial positionr→0,τ = {Δt, 2Δt, …, (N − 1)Δt} are time lags where Δtis the time difference between subsequent images and the average < · >tis taken over time. The resulting MSD is a function of...
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Here, we present chemically-detailed conformational movies of biological function, extracted data-analytically from experimental single-particle cryo-electron microscopy (cryo-EM) snapshots of ryanodine receptor type 1 (RyR1), a calcium-activated calcium channel engaged in the binding of ligands. The ...