Polymorphism—n.多态性、多形性 makecleartothisdefinition twosequencedDNAfragmentsfromdifferentindividuals,AAGCCTAtoAAGCTTA,containadifferenceinasinglenucleotide.hugequantity CurrentestimatesarethatSNPsoccurasfrequentlyasevery100-300bases.Thisimpliesinanentirehumangenomethereareapproximately10to30millionpotentialSNPs....
Single nucleotide polymorphism (SNPMitochondrial DNALiquid bead arrayScreeningThirty single nucleotide polymorphisms (SNPs) in mitochondrial DNA were investigated in 105 unrelated Japanese by liquid bead array technology which is a detection method using microsphere and a flow cytometer. Nineteen SNPs were ...
Background: Genome-wide association studies (GWASs) have identified some immune-related single-nucleotide polymorphisms (SNPs) to be associated with leprosy.Methods: This study investigated the association of 17 SNPs based on previously published GWAS studies with susceptibility to ...
A single nucleotide polymorphism (SNP) mutation in the miRNA binding regions of the 3′ UTR of any mRNA can radically affect its expression in many ways, such as by creating a new binding site for miRNA or by enhancing the stability of miRNA-mRNA complexes to increase binding of RISC ...
The humangene harbors a common single-nucleotide polymorphism (SNP) at codon 72, which yields an arginine-to-proline amino-acidic substitution () that modulates the apoptotic activity of the p53 protein. Previously, we found that this SNP controls neuronal susceptibility to ischemia-induced ...
IDH mutational status is required for proper diagnosis according to the WHO criteria revised in 2016. The single nucleotide polymorphism (SNP) rs11554137 (IDH1105GGT) at codon 105 of IDH1 has been reported in patients with several tumor types, including
(2013) Single nucleotide polymorphism genotyping using BeadChip microarrays. Curr. Protoc. Hum. Genet., Chapter 2, Unit 2 9.Lambert, G. et al. (2013) Single nucleotide polymorphism genotyping using BeadChip microarrays, Current protocols in human genetics / editorial board, Jonathan L. Haines .....
Single-nucleotidepolymorphismsHepatitisBvirusgenemutationMultiplexingelectrochemicalbiosensorOligonucleotide-incorporatednonfoulingsurfaces(ONS)abstractAnovelelectrochemicalDNAbiosensorforsingle-nucleotidepolymorphism(SNP)analysiswasdeveloped.Inthiswork,anoligonucleotide-incorporatednonfoulingsurface(ONS)wasconstructedtoresistnonspeci...
To establish 'personalized medicines' that can provide the right drug at the appropriate dose for each individual patient on the basis of genetic background, we have been building the infrastructure for a Japanese single nucleotide polymorphism (SNP) database of the genes encoding various enzymes, ...
(PG) embryos among our detected early embryos using single-nucleotide polymorphism (SNP)-separated allelic reads (Fig.1cand Supplementary Fig.2a). Then, we sought to determine whether the embryo abnormalities would cause aberrant embryo development. Notably, along the developmental trajectory inferred ...