single nucleotide polymorphism (SNP)genotypinghigh‐throughputInfinium assaygenome‐wide association study (GWAS)fine‐mappingfocused microarraysThe genotyping of single nucleotide polymorphisms (SNPs) has successfully contributed to the study of complex diseases more than any other technology to date. Genome-...
SNP，single nucleotidepolymorphism，即单核苷酸多态性。是指基因组DNA序列中由于单个核苷酸（A、T、C和G）的突变而引起的多态性。SNP广泛存在于人类基因组，其中发生频率约为1%或更高。包括单个碱基的转换、颠换、插入和缺失等，但通常所说 的SNP并不包括后两种情况。（转换是指C-T，在其互补链上则为G-...
(2013) Single nucleotide polymorphism genotyping using BeadChip microarrays. Curr. Protoc. Hum. Genet., Chapter 2, Unit 2 9.Lambert, G. et al. (2013) Single nucleotide polymorphism genotyping using BeadChip microarrays, Current protocols in human genetics / editorial board, Jonathan L. Haines .....
目的研究儿茶酚胺氧位甲基转移酶(COMT)基因单核苷酸多态性(SNP)位点Ala22/72Ser与北方汉族人群精神分裂症(SCZ)之间的关系。 2. Objective:To establish an accurate and rapid single nucleotide polymorphism(SNP)genotyping method of Panax ginseng and P. 目的:建立快速、准确的单核苷酸多态性(SNP)测定法鉴别人参...
We hypothesized that single-nucleotide polymorphism (SNP) array genotyping could provide superior resolution in comparison to karyotyping to facilitate rapid diagnosis and genotype–phenotype correlations in TS. Here, we present the first systematic comparison between the two methods and pro- vide ...
We recently introduced a generic single nucleotide polymorphism (SNP) genotyping method, termed DASH (dynamic allele-specific hybridization), which entails... M Jobs - 《Genome Research》 被引量: 480发表: 2001年 Systematic assessment of copy-number variant detection via genome-wide single nucleotide...
We use high-density single nucleotide polymorphism (SNP) genotyping microarrays to demonstrate the ability to accurately and robustly determine whether ind... SG Microarrays,N Homer,S Szelinger,... 被引量: 988发表: 2008年 Using Molecular Beacons to Detect Single-Nucleotide Polymorphisms with Real-...
One single nucleotide polymorphism(SNP) was obtained in rbcL gene that can divide the larix species into two groups. 获得了rbcL基因上的一个SNP标记可以将落叶松种子分成两组,结合线粒体特异片断f-13、B-11,可以对一些落叶松种子做出准确、快速的鉴别。 3. The single nucleotide polymorphism(SNP)of MMP...
1.Single nucleotide polymorphism (SNP) is the molecular marker for the third generation human genome map.单核苷酸多态性(SNP)是第三代的人类基因组作图的分子标记,它指由单个碱基交换,插入或缺失,引起人群中出现两种有微小差异的DNA序列。 3)SNP[英][,es en 'pi:][美]['?s '?n 'pi]单核苷酸多态性...
Objective:To establish an accurate and rapid single nucleotide polymorphism(SNP)genotyping method of Panax ginseng and P. 目的:建立快速、准确的单核苷酸多态性(SNP)测定法鉴别人参、西洋参及2种样本的混合物。3) single nucleotide polymorphism(SNP) genotyping 单核苷酸多态性(SNP)分型4...