Single nucleotide polymorphism means a polymorphism corresponding to a difference at a single nucleotide position (substitution, deletion, or insertion). It includes the detection of a single nucleotide change by a direct sequence protocol. SNPs occur in both coding and noncoding regions of th...
SNPs(single nucleotide polymorphism , SNP ,发音为 “snips”), 主要是指在基因组水平上由单个核苷酸的变异所引起的 DNA 序列多态性。它是人类可遗传的变异中最常见的一种。占所有已知多态性的 90% 以上。 SNP 在人类基因组中广泛存在,平均每 500 ～ 1000 个碱基对中就有 1 个,估计其总数可达 300 万个...
Single nucleotide polymorphism analysis of Korean native chickens using next generation sequencing data. Mol. Biol. Rep. 42:471-477.SEO D W,OH J D,JIN S,et al. Single nucleotide pol- ymorphism analysis of Korean native chickens using next generation sequencing data[J]. Mol Biol Rep, 2015,...
Subsequently, the reads were aligned against the reference sheep genome deposited in the NCBI (version Oar_v4.0) by using the Bowtie2 program (Langmead and Salzberg, 2012). Polymorphism detection and structural annotation The detection of polymorphisms was performed based on the position in the ...
关键词: genetics genotyping lung disease pharmacogenetics single-nucleotide polymorphism DOI: 10.1378/chest.06-2252 被引量: 33 年份: 2007 收藏 引用 批量引用 报错 分享 全部来源 免费下载 求助全文 掌桥科研 万方医学 dx.doi.org Europe PMC NCBI 查看更多 相似文献 参考文献 引证文献...
Many molecular genetic studies of human diseases involve determining the genotypes for single nucleotide polymorphisms. This chapter summarises a number of different techniques for the single nucleotide polymorphism genotyping which can be applied to MMP genes. The chapter also provides a protocol and tec...
Polymorphism—n.多态性、多形性 makecleartothisdefinition twosequencedDNAfragmentsfromdifferentindividuals,AAGCCTAtoAAGCTTA,containadifferenceinasinglenucleotide.hugequantity CurrentestimatesarethatSNPsoccurasfrequentlyasevery100-300bases.Thisimpliesinanentirehumangenomethereareapproximately10to30millionpotentialSNPs....
掌桥科研 Semantic Scholar 万方医学 NCBI (全网免费下载) NCBI 查看更多 相似文献 参考文献 引证文献Single-Nucleotide-Polymorphism Genotyping of Coxiella burnetii during a Q Fever Outbreak in The Netherlands. Coxiella burnetii is the etiological agent of Q fever. Currently, the Netherlands is facing the...
Genotype of UMOD rs13333226 SNPs and their association with the kidney survival of chronic kidney disease patients. UMOD, uromodulin; SNP, single-nucleotide polymorphism. Table III. Multivariate analysis of prognostic factors associated with the kidney survival time in chronic kidney disease patients by...
Ho PA, Kuhn J, Gerbing RB, Pollard JA, Zeng R, Miller KL, Heerema NA, Raimondi SC, Hirsch BA, Franklin JL: WT1 synonymous single nucleotide polymorphism rs16754 correlates with higher mRNA expression and predicts significantly improved outcome in favourable-risk paediatric acute myeloid leukaemia...