W.E. Moerner (born 1953, Pleasanton, California, U.S.) is an American chemist who won the 2014 Nobel Prize for Chemistry for his work with single-molecule spectroscopy, which paved the way for later work in single-molecule microscopy by American physicist Eric Betzig. Moerner and Betzig ...
Stochastic Optical Reconstruction Microscopy,STORM, is one of a family of Nobel Prize winning super-resolution Single Molecule Localization Microscopies (SMLM) for the visualization of biological systems with an optical resolution measured in the tens of nanometers (nm) in the x, y, and z directi...
doi:10.1093/nsr/nwt013Ding, S.-Y.Tian, Z.-Q.National Science ReviewSY Ding, ZQ Tian. A breakthrough in the chemical imaging of single molecule: sub-nm tip-enhanced Raman spectroscopy. National Science Review, 1(1), 4-5 (2014).
The workshop was opened with a talk by one of the early pioneers of single molecule research W.E. Moerner (Stanford University, USA). He clearly demonstrated that besides pure single molecule related research also super-resolution imaging and multimodal applications are important tools to solve rea...
生物单分子研究已成为21世纪生命科学领域的一个重点研究方向,在生命科学领域有着广泛的应用前景 Why we conduct single molecule or what single molecule can tell us? The Nobel Prize in Physics 1997 for development of methods to cool and trap atoms with laser light References Ch.Zander, J.Enderlein, ...
We review the use of luminescent nanoparticles in super-resolution imaging and single-molecule tracking, and showcase novel approaches to super-resolution imaging that leverage the brightness, stability, and unique optical-switching properties of these nanoparticles. We also discuss the challenges associate...
Through molecular engineering, we covalently integrated a single molecule Pd catalyst into nanogapped graphene point electrodes. We detected sequential electrical signals that originated from oxidative addition/ligand exchange, pretransmetallation, transmetallation and reductive elimination in a periodic ...
As a post-doctoral researcher at Stanford University and the University of California, Berkeley, Sivasankar worked with Steven Chu, the current US Secretary of Energy and co-winner of the 1997 Nobel Prize in Physics, to develop and build a single-molecule microscope. Supported by startup researc...
Imaging a single quantum dot when it is dark. Nano Lett. 9, 926–929 (2009). ADS CAS PubMed Google Scholar Celebrano, M., Kukura, P., Renn, A. & Sandoghdar, V. Single-molecule imaging by optical absorption. Nat. Photon. 5, 95 (2011); correction 12, 309 (2018). ADS CAS ...
Tailoring the electric-field waveform of ultrashort light pulses forms the basis for controlling nonlinear optical phenomena on their genuine, attosecond timescale. Here we extend waveform control from the visible and near-infrared—where it was previously demonstrated—to the mid-infrared spectral range...