Macrophage states change continuously under therapy Macrophages mediate resistance to ICT by becoming immunosuppressive under therapy (adaptive resistance); however, the effect of ICT on macrophage gene programs
Representative examples of the four major patterns of clonal evolution inTP53-sAML patients: bi-allelic mutations (b), hemizygous mutations (c), parallel evolution (d) andJAK2negative bi-allelic evolution (e). The numbers in parenthesis indicate the number of patients in each category...
The simplest explanation is that scRNA-seq sufficiently captured transcripts from engulfed oligodendrocytes (Mbp) or astrocytes (Gfap) in early postnatal PAM. Taken together, these data suggest that early postnatal PAM phagocytose newly formed oligodendrocytes and perhaps, to a lesser extent, astrocytes...
the crystal structure of a K+with a complete hydration shell—captured as part of the high-resolution structure of a bacterial K+channel (Zhou et al.2001) — has a diameter of roughly
If it does, then the beginning of the line is indented by the appropriate number of paragraph indents, but the verse number is set off slightly to the left to the space of a paragraph indentation (see the explanation below in the {\bf Recommended} paragraph). If you want to insert ...
It is to be understood that both the foregoing general description and the following detailed description of the present invention are exemplary and explanatory and are intended to provide further explanation of the invention as claimed. BRIEF DESCRIPTION OF THE DRAWINGS The accompanying drawings, which...
While, for purposes of simplicity of explanation, the methodologies are shown and described as a series of blocks, it is to be understood and appreciated that the disclosed aspects are not limited by the number or order of blocks, as some blocks may occur in different orders and/or ...
The probable explanation is that once intense vitellogenin synthesis was induced maximally in males after initial exposure to the EE2, it became difficult to observe any reductions within the relatively short period (21 days) of the experiment, because vitellogenin clears very slowly from the blood....
explanation for the increase in unmarried mothers in Americ A.One explanation is that the woman’s rights movement gave many women a new feeling of independenc E.Another explanation is the society is more willing to accept unmarried mothers than it did in the past.Unmarried mothers and their ...
Our data suggest that ECs from different origins (e.g. adult vs. embryonic; arterial vs. venous) may respond differently to FOXO3A deficiency and one possible explanation is that FOXO3A may regulate different downstream target genes in a cell type-dependent manner43 as multiple FOXO3A target ...