4a). The interaction intensity comparison diagram was then used to analyse the incoming interaction strength between the SC5 subcluster and the other beta cell subclusters (Fig. 4b). We found that the signals from SC2 to SC5 beta cells were the most highly enriched (Fig. 4b). For instance...
a, The diagram illustrates the identification of cell-type-unique and multiple cell-type-shared neighboring-region co-occupancy events. b-c, Heatmaps showing the cell-type-unique neighboring-region co-occupancy events (b) and multiple cell-type-shared neighboring-region co-occupancy events (c)....
Time-series single-cell RNA sequencing (scRNA-seq) datasets provide unprecedented opportunities to learn dynamic processes of cellular systems. Due to the destructive nature of sequencing, it remains challenging to link the scRNA-seq snapshots sampled at
A Venn diagram to show the activated regulons during differentiation from DoAP to AcAP, and those from DoPP to AcPP. The 61 shared regulons of the DoAP and AcAP (green and orange background), and the 32 shared regulons of the DoPP and AcPP (blue and orange background), and the 18 ...
(A) Schematic diagram of the binding specificity assay. Cells expressing differentially tagged Pcdh isoforms are mixed and assayed for homophilic or heterophilic interactions. A strict homophilic interaction is indicated by mixed red and green coaggregates between cells expressing only the identical isofo...
Deer antlers constitute a unique mammalian model for the study of both organ formation in postnatal life and annual full regeneration. Previous studies revealed that these events are achieved through the proliferation and differentiation of antlerogenic
11. Ramp mode: straight_line ramp,S_curve ramp two groups of acceleration /deceleration time with the range of 0.00-300.0s(m) 12. DC braking: DC braking frequency:0.00Hz to maximum frequency , braking time: 0.0-36.0s, braking action current value:...
Modulation System MCB Certification CE, RoHS, ISO Brand Citel SPD Type 2 Network 230/400 V Nominal Line Voltage 400 VAC Max. AC Operating Voltage 440 VAC Temporary Over Voltage 580 VAC Residual Current < 1 Ma Operating Current 0.5 Ma Nominal Discharge ...
With the rapid development of precision engineering and medical technology, the use of engineering methods for surgical intervention on single biological cells is an emerging technology in the field of medical applications. This development is in line with the trend of expanding modern therapies from ...
We tested the ability of AF647-p53 to bind the three DNA constructs diagrammed in Fig.1C using EMSAs. The wild type DNA consisted of the RE from the human GADD45 promoter, containing two 10 bp half-sites (gray boxes) with no spacing between. The mutant half site construct had one hal...