HoneyBADGER - [R] - HoneyBADGER identifies and infers the presence of CNV and LOH events in single cells and reconstructs subclonal architecture using allele and expression information from single-cell RNA-sequencing data. inferCNV - [R] - Part of the TrinityCTAT (Trinity Cancer Transcriptome ...
3c). We then quantified the contrast of each landed protein by fitting a complex-valued point spread function (PSF) model derived from the average PSF of all the landing events (Fig. 3d and Methods). Fig. 3: Single-protein holography. a, Dark-field and holographically reconstructed ...
These include four epidemic CoVs causing mild respiratory symptoms in human (i.e., HCoV-NL63, HCoV-229E, HCoV-OC43, and HCoV-HKU1) and two CoVs related to animal-to-human spillover events, including SARS-CoV and Middle East respiratory syndrome CoV. These six CoVs all originate from ...
On some single-page applications, you might see several History events occur simultaneously. That’s why you need to answer one more question. How many History events do you see when you navigate from Page A to Page B? Some websites may be coded in a particular way that w...
The application also provides government staff with direct access to all events held in the Legislature Press Theatre including Dr. Bonnie Henry's weekly press conferences on the COVID-19 outbreak. Today's News Online (TNO) is a news aggregation system that takes in news sources of varying typ...
Thus, where block boundaries reflect a small number of recombination events, genotypes will not be independent between adjacent blocks, and the optimal set of sites for a region that spans multiple blocks can be smaller than the sum of the optimal sets of sites when each block is considered ...
Although iCAFs and mCAFs were the major CAFs celltypes across 6 cancer types, different subtypes of CAFs still exhibited significant cancer preferences (Fig.2e and f). iCAFs were enriched in BRCA and CRC, whereas meCAFs were enriched in LIHC and OVCA (Fig.2f). The other two subtypes, es...
Clonal evolution is a landmark theory that attributes cancer pathogenesis to an evolutionary process driven by mutations and the selective advantages of subclones [39]. The identification of the pattern in cancer clonal evolution and the driver events that conferred selective advantages in tumor progres...
After enhancement by scCASE, the dropout events have been effectively imputed, and accessible patterns of different cell types can be effectively captured, again suggesting the profound proficiency of scCASE in interrogating and elucidating cellular heterogeneity. Moreover, correcting for sequencing depth ...
f Numbers of events detected for each time window on the full field and the ROI. Note that, in the range we investigated, the time window seems to have little influence on the resolution. The optimal value is found to be 30 ms, which is the value that was used in the manuscript (...