During mouse embryonic development, pluripotent cells rapidly divide and diversify, yet the regulatory programs that define the cell repertoire for each organ remain ill-defined. To delineate comprehensive chromatin landscapes during early organogenesis,
We report these 73 spatially significant peaks as a reference for future MCAO regulatory element studies. Moran’s I spatial autocorrelation analysis We performed a Moran’s I test to assess spatial autocorrelation between punch locations, wherein a higher Moran’s I value signifies a higher chance...
where [Math Processing Error]⊙ is the Hadamard (element-wise) product, and x represents the [Math Processing Error]N− dimensional vector on the graph, i.e. the gene expression values of a cell in this work. [Math Processing Error]h(Λ) is a diagonal matrix that is denoted as the ...
bottom inGandKare the magnified vessel elements and ray parenchyma cells. Scale bars, 25 μm. The illustrations for three cell type collection from transverse and tangential perspectives (D,E,H,I,L,M). InEandI, the white box represents a vessel element with empty lumen. InL, the pink box ...
Single-cell RNA sequencing (scRNA-seq) plays a pivotal role in our understanding of cellular heterogeneity. Current analytical workflows are driven by categorizing principles that consider cells as individual entities and classify them into complex taxon
Calibration beads, EQ™ Four Element Fluidigm Cat#201078; RRID: N/A UltraComp eBeads beads eBioscience Cat# 01-2222-42; RRID: N/A Seahorse XF Base RPMI pH 7.4 Agilent Technologies Part#103576-100; RRID: N/A TrueStain FcX (anti-mouse CD16/32 antibody (clone 93) BioLegend Cat#10132...
tested the specific contributions of each design element by implementing a set of SCALEX test-variants, each lacking an individual or a combination of the design elements, and evaluating their performance for single-cell data integration (“Ablation studies using test-variants of SCALEX” in ...
1B). Single-cells are hereby co-encapsulated with the microgels in water-in-oil emulsions and can be sorted further down in the microfluidic device. Cells trapped in a droplet are excited by an adjacent blue-laser optical emission fibre. If cells are viable at the moment of encapsulation, ...
Throughout this specification the word “comprise”, or variations such as “comprises” or “comprising”, will be understood to imply the inclusion of a stated element, integer or step, or group of elements, integers or steps, but not the exclusion of any other element, integer or step, ...
As used herein “another” or “other” may mean at least a second or more of the same or different claim element or components thereof. As used herein, the term “functional SWNT” refers to a single wall nanotube (SWNT) that has a functional pendant moiety or handle, such as a ...