单细胞空间转录组测序：从组织到单细胞 单细胞ATAC测序：单细胞表观基因组学水平染色质可及性 单细胞蛋...
RAPIDS 可用于 GPU 进行下游单细胞 RNA 测序(scRNA-seq)分析的一般可行性,这一可行性已在《使用 GPU 加速单细胞基因组分析》中得到证实。此外,该工作还产生了rapids-single-cell-examples GitHub repo,其中包含一系列由RAPIDS和NVIDIA Parabricks构建的示例。RAPIDS 是一个 GPU 的开源库套件,用于 Python 的加...
GPUs for single-cell analysis General feasibility of running downstream single-cell RNA sequencing (scRNA-seq) analysis on the GPU with RAPIDS and Scanpy has been shown in Accelerating Single-Cell Genomic Analysis with GPUs. This work resulted in the rapids-single-cell-examples GitHub repo, which...
基于以上问题,作者综述了目前scRNA-seq分析流程、步骤和方法(Figure 1),提出了一套目前最佳的实践分析流程,详见theislab/single-cell-tutorial. 这套分析流程在Jupyter–Ipython notebook 进行,包括R和python语言,可推荐作为一套分析模版。 Figure 1. Schematic of a typical single-cell RNA-seq analysis workflow. ...
图片来源:Zhang M J, Hou K, Dey K K, et al. Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data[R]. Nature Publishing Group, 2022. 2、通过scDRS分析可以得到什么 第一、鉴定表型相关的细胞类型,比如下图: ...
The metacells package implements the improved metacell algorithm[1]for single-cell RNA sequencing (scRNA-seq) data analysis within thescipyframework, and projection algorithm based on it[2]. The original metacell algorithm[3]was implemented in R. The python package contains various algorithmic improve...
图片来源:Zhang M J, Hou K, Dey K K, et al. Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data[R]. Nature Publishing Group, 2022. 2、通过scDRS分析可以得到什么 第一、鉴定表型相关的细胞类型,比如下图: ...
目前在蛋白质生物信息学、质谱学(MS)、下一代测序(NGS)、large-scale data handling and integration、metagenomics、系统生物学、生物统计学和RNAseq等方面拥有专业知识。NBIS致力于在生命科学实验室搭建生物信息学平台,在与研究小组密切合作的同时也会将一部分时间用来教授用户,以传播生物信息学知识。
Here we performed single-cell RNA-seq analysis of over 2,000 FGCs and their gonadal niche cells in female and male human embryos spanning several developmental stages. We found that female FGCs undergo four distinct sequential phases characterized by mitosis, retinoic acid signaling, meiotic prophase...
图片来源:Zhang M J, Hou K, Dey K K, et al. Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data[R]. Nature Publishing Group, 2022. 2、通过scDRS分析可以得到什么 第一、鉴定表型相关的细胞类型,比如下图: ...