lung; G, gill.bLung cell landscape of 53,605 cells from terrestrialized and freshwater lungfish. Cells are shown by Uniform Manifold Approximation and Projection and color-coded by cluster cell type. Each dot represents a cell, and different colors are associated with specific cell types. Vasc_...
BEIJING, Jan. 8 (Xinhua) -- Chinese experts have published a single cell spatio-temporal map of human limb development, shedding light on the cell evolution path and the determination process of cell spatial position in fetal limbs. Human limbs emerge during the fourth post-conception week as ...
Noisy gene expression is of fundamental importance to single cells, and is therefore widely studied in single-celled organisms. Extending these studies to multicellular organisms is challenging since their cells are generally not isolated, but individuals in a tissue. Cell–cell coupling via signalling...
scfetchprovides functions for users to downloadcount matricesandannotations(e.g. cell type annotation and composition) from GEO and some single-cell databases (e.g.PanglaoDBandUCSC Cell Browser).scfetchalso supports loading the downloaded data toSeurat. Until now, the public resources supported and ...
Table S1. Summary of Single-Cell Dataset and Clustering Information, Related to Figure 1 Table S2. Barcode RT Primer Information and Cell-Cycle Gene Sets, Related to STAR Methods, Figures 3C, 4B, and S5A Table S3. Differentially Expressed Genes and GO Terms of Female and Male FGCs, Related...
Empty Cell100 mg NAM500 mg NAM Empty Cell0 h48 hp value0 h48 hp value CRP (mg/dL) 0.19 ± 0.15 0.21 ± 0.23 0.83 0.18 ± 0.17 0.18 ± 0.17 0.80 Serum albumin (g/dl) 4.8 ± 0.2 4.7 ± 0.2 0.55 4.7 ± 0.2 4.7 ± 0.2 0.48 AST (U/L) 36 ± 9 33 ± 7 0.04 31 ± 8 ...
Acinar metaplasia is an initial step in a series of events that can lead to pancreatic cancer. Here we perform single-cell RNA-sequencing of mouse pancreas during the progression from preinvasive stages to tumor formation. Using a reporter gene, we ident
Single-cell transcriptome sequencing (scRNA-seq) has been employed to define cellular subtypes by revealing their specific transcriptional signatures. Compared with so-called ‘bulk RNA-seq’ studies of whole organisms or tissues, scRNA-seq has exceptional resolving power, being able to detect genes ...
Despite this limitation, we identified common processes that are altered upon AD in both organisms. Additionally, the publicly available and in-house single cell datasets from zebrafish are limited in number. This reduces the power for a more comprehensive comparison between zebrafish and human. The...
Such integration enhances the power of scRNA-seq analysis and facilitates the exploration of cellular heterogeneity across tissues and organisms. To integrate diverse omics data measured at the single-cell level, various methods including mapping, deconvolution, and multimodality fusion are employed. ...