18 2 一,背景 单臂试验(single arm trial,SAT)是指设计为开放,不 设立平行对照组的一种临床试验.在抗肿瘤新药研发中,单 臂试验最初常用于传统的细胞毒类抗肿瘤新药早期探索性 阶段,通常采用最大耐受剂量(maximum tolerated dose,MTD) 作为试验药的剂量选择依据,利用单臂试验对研究人群和给 药方案的有效性和安全...
single-arm clinical trial 肿瘤 关键词:肿瘤临床研究术语基础研究 词汇介绍 拓展阅读 解析 Single英 /'sɪŋg(ə)l/美 /'sɪŋɡl/ 释义adj. 单一的;单身的;单程的;n. 一个;单打;单程票;vt. 选出;vi. 击出一垒安打 同根词singly adv. 逐一地;个别地;各自地;直截了当地;singleness n. 单...
18 2 一,背景 单臂试验(single arm trial,SAT)是指设计为开放,不 设立平行对照组的一种临床试验.在抗肿瘤新药研发中,单 臂试验最初常用于传统的细胞毒类抗肿瘤新药早期探索性 阶段,通常采用最大耐受剂量(maximum tolerated dose,MTD) 作为试验药的剂量选择依据,利用单臂试验对研究人群和给 药方案的有效性和安全...
Phase 2, single arm clinical trial to evaluate the safety and activity of oregovomab and niraparib as a combinatorial immune priming strategy in subjects with platinum sensitive recurrent ovarian cancer: FLORA-4 study.doi:10.1200/JCO.2024.42.16_suppl.5586...
【3.2.1】单臂试验(single arm trial, SAT) 单臂试验(single arm trial, SAT) 在我们临床研究中,常用的是为试验组或病例组设计一个参比的对照组。对照组的形式,在ICH E10文件中提供了五种类型: 安慰剂对照 空白对照 剂量对照 阳性药物对照 外部对照
BEIJING, Dec. 29 (Xinhua) -- Chinese researchers have completed the First-in-Man (FIM) clinical trial using a single-arm laparoscopic surgical robot in China, according to the Beijing Friendship Hospital affiliated to Capital Medical University. ...
L08A Single Arm Clinical Trial to Assess the Efficacy and Safety of Panitumumab (Vectibix ) in combination with FOLFOX4 Chemotherapy as 1st line treatment in Subjects with Metastatic Gastric or Gastroesophageal Junction adenocarcinoma (V... R Casaretti,P Comella,C Carlomagno,... - 《Annals of ...
An academic prospective single-arm phase II clinical trial for evaluation of advanced functional neuroimaging and molecular markers during bevacizumab/irinotecan therapy for recurrent malignant gliomaPelvisRadiotherapyToxicityEnteritisGlutaminePurpose Our primary endpoint is to determine the ...
Psoriasis is a common, chronic immune-mediated systemic disease that had no effective and durable treatment. Mesenchymal stem cells (MSCs) have immunomodulatory properties. Therefore, we performed a phase 1/2a, single-arm clinical trial to evaluate the safety and efficacy of human umbilical cord-der...
2.1. Trial design The AMCAD study is an investigator-initiated, multicenter, phase II single-arm trial. Approval for the study protocol and related documents was granted by the institutional review board of the National Cerebral and Cardiovascular Center and Mie University. This study will be condu...