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leading the gene expression to programmable inhibition and subsequently re-activation via toehold-mediated strand displacement. The regulatory strategy from Css DNA can thus expand the molecular toolbox for the realization of synthetic regulatory networks with potential applications in genetic diagnosis and...
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Single-molecule FRET microscopy and hidden Markov modeling analysis with the full-length SAM-I riboswitch reveal the existence of multiple conformational states and the effects of Mg2+ and SAM binding on their dynamics and population shifts. S-adenosyl-L
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