Salomon, Internal dynamics of simple molecules revealed by the superfine and hyperfine structures of their infrared spectra, in: T.W. Hansch, Y.R. Shen (Eds.), Laser Spectroscopy VII, Springer-Verlag, 1985, pp. 108-114.Ch.J. Borde, J. Borde, Ch. Breant, Ch. Chardonnet, A. van ...
The iDISCO protocol combines the steps of sample preparation and immunolabeling with stable fluorophores outlined above, together with a slightly simplified 3DISCO procedure, to permit volume imaging of labeled molecules and structures in large intact samples. It is detailed in Data S2. Application of...
One, partial solution adopted by cells is to organise the phenotype not at the level of a myriad molecules or macromolecules but at the higher level of a small number of hyperstructures, which are spatially extended assemblies of molecules and macromolecules that have one or more functions within...
The protein molecule was immersed in a 70.4 × 65.9 × 70.6 Å3 periodic box of TIP3P water molecules (7680 water molecules and 25,501 atoms in total). The long-range electrostatic interactions were treated using the particle-mesh Ewald method. The systems were energy minimized by the...
Most of the previous CRISPR imaging applications focused on visualizing repetitive DNA elements, where the signal amplification from multiple bound dCas9 molecules facilitates detection. Although significantly more challenging, dCas9 can also be used to tag non-repetitive DNA elements, when programmed with...
Simple diffusion is the passive movement of molecules from an area of higher concentration to an area of lower concentration. This process occurs without the need for energy input and is driven by the concentration gradient. In simple diffusion, molecules move freely across a membrane, spreading ou...
A Simple Algorithm for Unique Representation of Chemical Structures—Cyclic/Acyclic Functionalized Achiral Moleculescomputers in chemistry, computer programsChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ...
The spin-projected extended Hartree-Fock method Adv. Quantum Chem., 12 (1980), pp. 189-262 View in Scopus Google Scholar 24 a F. Turec̆ek Proton affinity of dimethyl sulfoxide and relative stabilities of C2H6OS molecules and C2H7OS+ions. A comparative G2(MP2) ab initio and density...
RNA catalytic and binding interactions with proteins and small molecules are fundamental elements of cellular life processes as well as the basis for RNA therapeutics and molecular engineering. In the absence of quantitative predictive capacity for such bioaffinity interactions, high throughput experimental...
[AlO4]−, as the presence of water molecules near Al typically narrows the Al signal.26All Al species are susceptible to polarization transfer, as attested by the comparison between the27Al MAS and CP-MAS signals (see Supplementary Material Fig.S4d). Heating the altered glass at higher ...