TLR5 activation induces secretory interleukin-1 receptor antagonist (sIL-1Ra) and reduces inflammasome-associated tissue damage . Mucosal Immunol 4 : 102–111, 2012.Carvalho FA, Aitken JD, Gewirtz AT, Vijay-Kumar M. TLR5 activation induces secretory interleukin-1 receptor antagonist (sIL-1Ra) and...
Crosslinking of sIL-1RAcP to cell surface bound IL-1RI was only possible in the presence of IL-1. We conclude that sIL-1RAcP can form a weak complex with IL-1RI, while not inhibiting biological IL-1 activity. 展开 会议名称: Herbsttagung der Gesellschaft für Biochemie und Molekular...
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TLR5 activation induces secretory interleukin-1 receptor antagonist (sIL-1Ra) and reduces inflammasome-associated tissue damage. Carvalho F A,Aitken J D,Gewirtz A T,Vijay-Kumar M. Mucosal immunology . 2010Carvalho FA, Aitken JD, Gewirtz AT, Vijay-Kumar M. 2011. TLR5 activation induces ...
Soluble interleukin-1 receptor antagonist (sIL-1RA), interleukin (IL)-1alpha, IL-1beta, IL-2, sIL-2R, IL-3, IL-4, IL-6, sIL-6R, IL-10, tumor necrosis factor (TNF)-alpha, transforming growth factor (TGF)-beta(2) and interferon ...
本发明提供了一种重组腺相关病毒AAV2/2sFLT1P2AsIL1Ra及其构建方法和应用,选用2/2型腺相关病毒(AAV2/2)构建了治疗组AAV2/2sFLT1P2AsIL1Ra.其中sFLT1蛋白会中和VEGFA并阻止其与其膜结合受体VEGFR2的异二聚化,从而阻止VEGFA介导的血管生成.sIL1Ra为IL1受体拮抗蛋白(IL1Ra)的可溶形式,能够与IL1竞争IL1受体(IL...
394 TLR5-Mediated Expression of Endogenous IL-1β Antagonist, Sil-1ra, Protects Against InflammationThe well-being of the intestine and its host requires that this organ execute its complex function amid colonization by a large and diverse microbial community referred to as the gut microbiota. A ...
Modulation of Arthritis through overexpression of soluble inter-leukin-1 receptor accessory protein (sIL-1RAcP): a novel inhibitor of interleukin-1, distinct from IL-1Rareactive oxygen speciespulmonary fibrosismatrix metalloproteinasesExposure of mature cotyledonary somatic embryos of Picea abies to low ...
Effect of IL-15 on the secretion of IL-1beta, IL-1Ra and sIL-1RII by PMN from cancer patients. Cytokine. 2001 Dec 7; 16 (5):173–177.Jablonska E, Piotrowski L, Kiluk M, Jablonski J, Grabowska Z, Markiewicz W. Effect of IL-15 on the secretion of IL-1b, IL-1Ra and sIL-1...
Serum levels of IL-10, IL-6, IL- 1ra, and sIL-2R in patients with psoriatic arthritis. Rheumatol Int 2000;19(3):101-105.Elkayam O, Yaron I, Shirazi I et al. Serum level of IL- 10, IL-6, IL-1ra and sIL-1R in patients with psoriatic arthritis. Rheumatol Int 2000;19(3):101...