In myeloma, the abnormal plasma cells eventually invade and destroy the outer hard layer of bone. The destruction of bones (osteolysis), typically occurring in small areas at different sites, may lead to serious problems. Even a small osteolytic lesioncan cause the bone to break -- or more ...
Amyloidosis is a disease characterized by the deposition of beta-sheet fibrillar protein aggregates in various tissues; the deposition can be localized or involve multiple organs, such as the liver, spleen, kidneys, heart, nerves, and blood vessels [70]. The main forms of amyloidosis affecting ...
Healthcare experts also use AI to detect cardiovascular diseases based on the heart’s dimensions. Researchers at Cedars-Sinai Medical Centerhave developed an AI toolfor detecting diseases — hypertrophic cardiomyopathy and cardiac amyloidosis — you might overlook when examining the heart. Can AI detec...
Multiple myeloma (MM)-related renal failure is a specific entity that includes cast nephropathy, amyloidosis, and light-chain nephropathy [3]. MM patients are also at risk for hypercalcemia-associated renal failure. Postrenal causes of renal failure are more common among cancer patients than in ...