The Black Death, which swept through Europe in the 14th century, had a significant impact on the European economy mainly because _. A. it increased the price of agricultural products due to a shortage of labor B. it made all the trade routes completely blocked C. it led to the immediate ...
Since many of these fast-growing trees germinated in the early-14th century and the number of dated buildings drops dramatically several decades before the plague, the Black Death can hardly be the only reason for the population decline in Norway and one plausible explanation is that some ...
“Many of the changes below are based on data and feedback from Weekend 1,” Treyarch explained in ablog post, “but rest assured we are also taking this into account as we look ahead to launch. We’ll be sharing more about what’s to come in the weeks after Wee...
Amino acid metabolism plays a pivotal role in tumor microenvironment, influencing various aspects of cancer progression. The metabolic reprogramming of amino acids in tumor cells is intricately linked to protein synthesis, nucleotide synthesis, modulation of signaling pathways, regulation of tumor cell meta...
Europe during the 16th century went through many changes. Due to the Renaissance and Humanism, Europe would see a great change in its structure, thus throwing itself into an age of creative individualism. The Renaissance infused Humanism into government and gave every man a right to his own wil...
The R soft- ware package limma26 was used to achieved differential analysis on 91 control and 122 IPF samples of GSE47460, genes differentially expressed with P values < 0.05 and fold changes > 1.5 or < 2/3 were visualized using an R pack- age heatmap. The metascape ...
Sports requiring sudden changes in direction, including football, rugby, ice hockey, and tennis, can cause repeated stress on the pubic symphysis and sup- porting muscles, thereby leading to reduced mobility and loss of sports activity (Minnich et al. 2011; Mosler et al. 2018; Orchard ...
Since these estimates are used in the test statistics to assess the statistical significance of the observed fold change, proteins exhibiting a large fold change are often declared non-significant because of a large sample variance, while at the same time small observed fold changes might be ...
Abstract Cancer and coronary artery disease (CAD) are two of the most common causes of death, and they frequently coexist, especially as the world’s population ages. CAD can develop prior to or following cancer diagnosis, as well as a side effect of cancer treatment. CAD develops as complex...
In hematopoietic cells, genetic changes involving protein tyrosine kinases leading to deregulation of intracellular signaling pathways, have been linked to leukemogenesis as well as to progression of the leukemic disease.3 Activation of the FMS-like receptor tyrosine kinase 3 (FLT3), expressed on early...