Imagine you believe the mean human body weight is 72kg. The mean human weight isn't a random number, but it's very hard to measure directly. You are forced to take a sample, and compute the sample mean. This sample mean is a random variable, and it will have different values for ...
RESULTS: The total number of cases was 80. Out of these, 72 were males and 8 were of females. Maximum number (30) of injured was between the ages of 20 to 30 years.40 cases (50%) were from Shikarpur distri...
This means there is a .0312 chance that the base quality scores of the reference allele and alternate allele are the same. Assuming a p-value cutoff of 0.05, meaning there is less than 5% chance there is no difference in the two groups, and greater than or equal to 95% chance that th...
In a recent article, a team of 72 authors proposed another solution. They recommended that psychologists should reduce the probability of a type-I error from 5% (1 out of 20 studies) to 0.5% (1 out of 200 studies). This recommendation is based on the belief that the replication crisis i...
Origin and paleoenvironmental significance of FeMn nodules in the Holocene perialpine sediments of Geneva Basin, western Switzerland Author links open overlay panelBranimir Šegvić a, Stéphanie Girardclos b c, Giovanni Zanoni a, Carlos Arbiol González d, Tara Steimer-Herbet e, Marie Besse e...
Truth claims in the medical literature rely heavily on statistical significance testing. Unfortunately, most physicians misunderstand the underlying probabilistic logic of significance tests and consequently often misinterpret their results. This near-un
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Second, the confidence limits surrounding the HR estimates in the LOWESS plot are a function of the number of primary efficacy outcomes, which in turn depends on the trial sample size. It should therefore be acknowledged that the time to statistical significance of the clinical benefit may be a...
ongoing NA therapy in cHBV patients meaningfully reduces HBsAg after the end of the treatment period. I am impressed with the number of patients that qualified to stop NA therapy in the VTP-300 group and the clear separation in HBsAg levels between the treatment arm and placebo at Week 72....
HER-2/neu-targeted therapy has been successfully used in advanced gastric cancer, but the role of HER-2/neu in the prognosis of gastric cancer is not yet clear. In this study, we investigated the correlation between HER-2/neu expression and amplification