Glycolysis is a glucose breakdown pathway that is less efficient but faster, providing sufficient energy for cells in low oxygen environments. In the tumor microenviron- ment (TME), cancer cell glycolysis is particularly active, even in conditions of high oxygen concentration. This phenomenon of ...
Results: Inhibition of ABC transporters, especially ABCB1, improved drug efficacies. Staple GBM phenotypes, such as GBM stem cells and increased activation of the PI3K/Akt/NF-κB pathway, have been implicated in the expression of several ABC transporters. Using the datasets in The Cancer Genome ...