It is caused by the release of the tetanospasmin neurotoxin of Clostridium tetani, causing high mortality varying from 40 to 80% [1]. In neonatal tetanus cases, even with treatment, the case fatality rate can be 80–90%, accounting for significant preventable deaths [1]. WHO estimated that...
The mean values of IL-8, cTnI, CPK, CPK-MB and LDH were significantly higher in severe cases both on admission and on follow-up comparing with moderate cases. The case fatality rate was 12.5% and all were from severe cases with toxic myocarditis. The non-survivors victims showed ...
Some of the results pointed towards AOD potentially being a factor in estimating the coronavirus fatality rate. The models performed better using the data collected during the complete exposure period, which showed higher AOD values contributed to an increased significance of AOD in the models. ...
A well-balanced ion channel trafficking machinery is paramount for the normal electromechanical function of the heart. Ion channel variants and many drugs can alter the cardiac action potential and lead to arrhythmias by interfering with mechanisms like ion channel synthesis, trafficking, gating, permeat...
while a consistent dysregulation has also been observed in the CSF, evidenced by a differential expression profile of circRNAs identified in the CSF compared among COVID-19 case, healthy controls, and cases with neurological disease.39Considering the tissue- and cell-specificity of the circRNAs expre...
In the specific case of an ion channel, trafficking is understood as the set of processes encompassing the movement and localization of the channel during its life cycle. It includes the steps from its synthesis, forward movement and anchoring to the plasma membrane, and subsequent retrograde inter...
(Fig.1), highlighting the integral role of WTD in vector ecology. Managing WTD populations is crucial for mitigating these cascading effects on ecosystems, wildlife, and human health. The density thresholds for disease transmission, particularly in the case of tick-borne illnesses, underscore the ...
The mean values of IL-8, cTnI, CPK, CPK-MB and LDH were significantly higher in severe cases both on admission and on follow-up comparing with moderate cases. The case fatality rate was 12.5% and all were from severe cases with toxic myocarditis. The non-survivors victims showed ...
There were two cases of maternal deaths in this study, giving a case fatality rate of 6.1%%. Conclusion. aEuro integral Rupture of the gravid uterus is still a problem in Nigeria. A proactive approach to preventing prolonged obstructed labor and curbing the injudicious use of oxytocics through...
Case Presentation: The patient was a woman with progressive thrombocytopenia. She had a strong family history of thrombocytopenia and hematologic malignancies with a high fatality rate. We detected that genomic RUNX1 had consecutive DNV (c.352G>T and c.352-1 G>C) at its splice site, ...