Prognostic significance of Auer rods in childhood acute myelogenous leukemia: results of the studies AML-BFM-78 and 83. Med Pediatr Oncol. 1989;17:202-209.Ritter J, Vormoor J, Creutzig U, Schellong G (1989) Prognostic significance of Auer rods in childhood AML: results of the studies AML...
Patients at standard risk (SR) were defined as having favorable morphology (French-American-British [FAB] classification M2 with Auer rods, M3, or M4Eo) and blast cell reduction in the bone marrow on day 15 to less than 5% (not obligatory for FAB M3). All other patients were considered ...
Bone marrow examination on day 27 post-therapy showed a hypercellular marrow and many maturing granulocytes containing Auer rods (lower left), but no hypergranular promyelocytes or faggot cells or increase in blasts. Thirteen per cent of the nuclei were positive for PML-RARA by FISH (lower ...
Significance of persistent Auer rods and cytogenetic abnormality after first cycle of therapy for acute promyelocytic leukaemiadoi:10.1111/j.1365-2141.2007.06541.xBakul I. DalalDepartment of HematopathologyHelene BruyereDepartment of HematopathologyMichael J. Barnett...
There were no differences between TdT+ as compared with TdT-negative (TdT-) patients with respect to age, sex, French-American-British (FAB) classification, or the presence of Auer's rods. Remission induction rates were higher for the TdT- patients, with 68% v 48% for the TdT+ patients...
Auer rodsBone marrowDysgranulopoiesisMorphologyPromyelocytic leukemiaRemission statusIndian Journal of Hematology and Blood Transfusion -doi:10.1007/s12288-021-01493-yHarpreet.VirkDepartment of Hematology, Postgraduate Institute of Medical Education & Research, Level 5, Research Block A Sector 12, Chandigarh...
The proportion of positive blasts and of cases with Auer rods in acute myeloid leukaemia (AML) was significantly greater with DAB than with benzidine. In addition, Phi bodies were demonstrated in AML blasts only when DAB was used; Phi bodies were also observed in two out of seven cases of ...
Of 155 consecutive cases studied by cytochemical staining methods, 14 were characterized by 4% to 15% (median 6%) myeloperoxidase-positive blasts. All 14 cases showed reactivity to Sudan black B stain, and 7 had Auer rods. The morphological subtypes of leukemia were M1 (8 cases), M2 (3),...
Dual staining of individual blasts demonstrated simultaneous expression of myeloperoxidase (MPO) (including Auer rods) in association with either T-11, CALLA, or terminal deoxynucleotidyl transferase. Blasts from one patient with ANLL demonstrated T cell receptor gene rearrangement, while blasts from ...
Expression of lymphoid-, progenitor- and most myeloid-associated antigens had no influence on the prognosis, whereas the outcome was significantly better for children with M2 with Auer rods, M3, or M4Eo or for those with the associated karyotypes t(8;21);t(15;17) and inv(16) than for ...