The scenarios for DDR inhibitors in clinic have been portrayed as: synthetic lethality, replication stress, and potentiation of chemo- or radio- therapy.11Synthetic lethality is described as malfunction in one certain DDR mechanism renders cells more reliant on other somewhat redundant DDR pathways to...
The scenarios for DDR inhibitors in clinic have been portrayed as: synthetic lethality, replication stress, and potentiation of chemo- or radio- therapy.11Synthetic lethality is described as malfunction in one certain DDR mechanism renders cells more reliant on other somewhat redundant DDR pathways to...