While the length of the linker does not matter, the insertion of a small, stably folded domain between these two interaction sites is detrimental to σ54 activity in vivo. This is consistent with the threading of the AID and linker by the transcriptional activator, which would not be ...
SummaryThe transcription factor sigma‐54 (σ54) is a sequence‐specific DNA‐binding protein that directs RNA polymer a se to a particular class of promoter. The interaction of σ54with promoter DNA has been analysed by protein‐DNA crosslinking and enzymatic and chemical proteolysis. Direct phy...
The dejitter circuitry is automated and does not require interaction or control from the user. Rev. C | Page 32 of 202 Data Sheet ADAU1462/ADAU1466 Master Clock, PLL, and Clock Generators Registers An overview of the registers related to the master clock, PLL, and clock generators is ...
Differe:'lt fJ -subunits determine G-protein interaction with transmembrane receptors and {J3) are selectively involved in the signal transduction cascades ftirvoemly,mtousvcoalrtiangice-Mde4pe(nredfe.n4t )Caan2d+ somatostatin channels. receptors, respec- We have established nuclear microinjection ...
The dejitter circuitry is automated and does not require interaction or control from the user. Master Clock, PLL, and Clock Generators Registers An overview of the registers related to the master clock, PLL, and clock generators is listed in Table 24. For a more detailed description, see the...
All studies are consistent with the assumption that promoter escape reduces the lifetime of the sigma-core interaction from very long at initiation (too long to be measured in a typical biochemical experiment) to a shorter, measurable lifetime upon transition to elongation. ...
Small molecule AX-024 reduces T cell proliferation independently of CD3ϵ/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. Kirsten Richter et al. The Journal of biological chemistry, 295(23), 7849-7864 (2020-04-23) ...
In fact, PHYB promotes the accumulation of HMR/PAP5/pTAC12 via direct interaction71. Moreover, because HMR/PAP5/pTAC12 and PAP8/pTAC6 are also dual-targeted to the nucleus and plastid and participate in both nuclear PHY signaling and PEP assembly (Fig. 9)72,73,74, their subcellular ...
Maurice T, Urani A, Phan V-L, Romieu P (2001) The interaction between neuroactive steroids and the σ1 receptor function: behavioral consequences and therapeutic opportunities. Brain Res Rev 37:116–132 CAS PubMed Google Scholar Maurice T, Martin-Fardon R, Romieu P, Matsumoto RR (2002) ...
The interaction between NifA and RNAP-σ54can be stimulated byIHF(integration host factor). Originally, IHF was described as a factor required for integration of phage λ DNA into the chromosome ofE. coli.IHF is a small DNA-binding protein belonging to the family of prokaryotic histone-like ...