Provided are an agent for reducing side effects in cancer treatment by administering sorafenib or a pharmacologically acceptable salt thereof, and an agent for enhancing anticancer action by administering sorafenib or a pharmacologically acceptable salt thereof. This is the issue. As a solution, ...
The incidence of adverse effects (AEs) due to sorafenib (Nexavar, Bayer/Onyx) appears to be considerably higher in patients with differentiated thyroid cancer (DTC) than in patients with renal cell or hepatocellular cancer, and these AEs frequently lead to dose reductions and even discontinuation o...
Common side effects of regorafenib may include:diarrhea, nausea, stomach pain; loss of appetite, weight loss; increased blood pressure; fever, infection; abnormal liver function tests; pain or redness in your mouth or throat, hoarse voice; or feeling weak or tired....
Cutaneous side effects of sorafenib and sunitinib. Ann Dermatol Venereol. 2008;135(2):148–53; quiz 147, 154. Article PubMed CAS Google Scholar Lacouture ME, Reilly LM, Gerami P, Guitart J. Hand foot skin reaction in cancer patients treated with the multikinase inhibitors sorafenib and ...
Cabometyx comes in the form of a tablet (20, 40 and 60 mg) and is used to treat advanced renal cell carcinoma (RCC), advanced RCC as a first-line treatment in combination with nivolumab, hepatocellular carcinoma (HCC) in patients who have previously been treated with sorafenib, certain type...
Nexavar (sorafenib) Thalidomide Veglin Studies show that Avastin is the best anti-angiogenesis drug for mesothelioma. No other anti-angiogenesis drug has shown as much promise in trials as Avastin. Combining Avastin with chemo improves overall survival rates according to research. Side Effects of Ant...
OPDIVO, in combination with ipilimumab, is indicated for the treatment of adult patients with hepatocellular carcinoma (HCC) who have been previously treated with sorafenib. This indication is approved under accelerated approval based on overall response rate and duration of response [see Clinical Studie...
Common side effects of Lenvima include: high blood pressure(hypertension), fatigue, diarrhea, joint and muscle pain, decreased appetite, weight loss, nausea, inflammation of the mouth and lips, headache, vomiting, protein in the urine, palmar-plantarerythrodysesthesia (PPE) syndrome, ...
-Hepatocellular carcinoma previously treated with sorafenib. Usual Adult Dose for Hepatocellular Carcinoma: 160 mg orally once a day for the first 21 days of each 28-day cycle -Lowest Dose: 80 mg per day -Duration of Therapy: Until disease progression or unacceptable toxicity ...
Common lenvatinib side effects may include: bleeding; stomach pain,nausea, vomiting, diarrhea; loss of appetite,weight loss; abnormal thyroid function tests; muscle or joint pain; pain and burning when you urinate; swelling in your arms and legs; ...