Targeting the pro-survival side-effects of androgen-deprivation therapy in prostate cancerIn this paper, Bennett et al. [1] report the effects of an anti-androgen drug on autophagy and the subsequent impact on response to androgen-deprivation therapy alone or combined with exiting chemotherapeutic ...
Vantas (histrelin acetate) is a medication implant used to deliver the medicine histrelin to your body continuously for 12 months to relieve the symptoms of prostate cancer, but it is not a cure. Serious side effects of Vantas include causing an increase in testosterone during the first week ...
Many men who have advancedprostate cancerexperience side effects. Some of these side effects result from the treatments used to slow the spread ofcancer. Other side effects come from the disease itself. Understanding these side effects can relieve fears and help you cope better. So can being an...
which is a protein on the membrane of osteoclasts that is essential for their formation, function, and survival. This inhibits osteoclast formation, which decreases bone resorption and increases bone mass and strength in both cortical (hard bone) and trabecular (spongy bone) bone. Prolia is a mo...
Ibrance is used to treat HR-positive, HER2-negative breast cancer in postmenopausal women or men that has spread to other parts of the body. Ibrance is used in combination with an aromatase inhibitor or fulvestrant. Includes Ibrance side effects, interac
Xtandi (enzalutamide) is anandrogenreceptor inhibitor indicated for the treatment ofprostate cancerin patients who have previously receivedDocefrez(docetaxel). What Are Side Effects of Xtandi? Xtandi may cause serious side effects including: hives, ...
Common side effects of denosumab include: Prolia Back pain Pain in the extremities Musculoskeletal pain Sciatica Bone pain Joint pain (arthralgia) Spinalosteoarthritis Muscle pain (myalgia) Weakness (asthenia) Upper respiratory tract infection Pneumonia ...
enhancing the translation of the cell surface-bound cytokine interleukin-1α (IL-1α), mTOR promotes the senescence- associated secretory phenotype mTOR is a Ser/Thr kinase that senses nutrient and growth signals and regulates many processes including cell proliferation, cell survival and autophagy. ...
Tell your doctor if you have rare but serious side effects of Cialis including: a painful or prolonged erection lasting 4 or more hours; sudden decreased vision (including permanent blindness, in one or both eyes); a sudden decrease or loss of hearing, sometimes withringing in the earsand di...
the confirmatory TROPiCS-04 study didnotmeet the primary endpoint of overall survival (OS) in the intention-to-treat (ITT) population. Therefore,Gilead plans to voluntarily withdraw the accelerated approval for Trodelvy in metastatic urothelial cancer.This decision does not affect the other approved ...