Expect additive negative inotropic effects of Camzyos and other drugs that reduce cardiac contractility. In the EXPLORER-HCM trial, 119 of 123 patients who received Camzyos received concomitant therapy with beta blockers (n=94), verapamil (n=19), or diltiazem (n=6). Avoid concomitant use of...
PSVT is caused by abnormal functioning of the cardiac electrical circuit. Adenosine restores normal rhythm in PSVT by acting on the adenosine receptors in the atrioventricular node, slowing down the impulse conduction time and interrupting abnormal re-entry pathways of electrical impulses in theAV nod...
The most important treatment-emergent adverse effects werehypotension, asystole/cardiac arrest/electromechanical dissociation (EMD), cardiogenic shock, congestive heart failure,bradycardia, liver function test abnormalities, VT, and AV block. Overall, treatment was discontinued for about 9% of the patients ...