2.side effect- any adverse and unwanted secondary effect; "a strategy to contain the fallout from the accounting scandal" fallout consequence,effect,result,upshot,outcome,event,issue- a phenomenon that follows and is caused by some previous phenomenon; "the magnetic effect was greater when the rod...
Extrapyramidal symptoms were more prevalent with use of the extended-release IM injection compared with oral formulations (18.4% versus 11.7%). Extrapyramidal disorder occurred most frequently with 30 mg oral doses, while the disorder occurred in 9.1% of patients given 10 mg oral doses. ...
The most commonly reported treatment-emergent EPS-related adverse events ( > 2%) in any treatment group in the double-blind phase of the study (Invega Sustenna versus placebo) were hyperkinesia (3.7% vs. 2.9%), parkinsonism (3.0% vs. 1.8%), and tremor (1.2% vs. 2.4%). Dystonia ...
Extrapyramidal symptoms were more prevalent with use of the extended-release IM injection compared with oral formulations (18.4% versus 11.7%). Extrapyramidal disorder occurred most frequently with 30 mg oral doses, while the disorder occurred in 9.1% of patients given 10 mg oral doses. ...
evaluated in 715 patients in second-line monotherapy studies, which included 537 patients with advanced RCC. The data described [seeClinical Trials Experience] reflect exposure to INLYTA in 359 patients with advanced RCC who participated in a randomized clinical study versus sorafenib [seeClinical ...
The convenience and efficacy of the single dose oral tablet of fluconazole regimen for the treatment of vaginalyeastinfections should be weighed against the acceptability of a higher incidence of drug related adverse events with DIFLUCAN (26%) versus intravaginal agents (16%) in U.S. comparative ...
1Citations Abstract Skin, hair, and nails are almost always modified by systemic cancer therapies. These changes can sometimes result in severe adverse events, but most of the patients present with light and moderate skin side effects. Nevertheless, these dermatologic manifestations can significantl...
Early Versus Late Side Effects The “therapeutic ratio” describes the balance between tumor kill and injury to healthy normal tissues and organs (Figure 7.9). All cancer therapies developed to date are associated with a spectrum of early and lateadverse effects, also known as toxicity, safety, ...
Ten articles reportedadverse effects[2–4,6,7,10–13,15]with quite varied results. Of the seven studies that evaluatedtopical administration[3–7,10,13], three described genitalpigmentationas an adverse effect[3,10,13]. This alteration was not described after intramuscular application. Two articl...
It is said that virtually all patients treated with interferon alfa experience some adverse effect(s) at some time during therapy [33]. In fact, the literature on side effects to interferons is voluminous and probably greater than all the other approved, non mAb biologics literatures put together...