The recent development of a database on side effects, the side effect resource (SIDER), is a first step in documenting the relationship between drugs and their side effects. It is, however, insufficient to simply find the association of drugs with biological processes; that relationship is ...
We also used the Side Effect Resource (SIDER) database11to evaluate model performance. The SIDER database contained associations between marketed drugs and their side effects. However, frequency information was provided for only 39.9% of drug-side effect pairs, which is insufficient for use in the...
The recent development of a database on side effects, the side effect resource (SIDER), is a first step in documenting the relationship between drugs and their side effects. It is, however, insufficient to simply find the association of drugs with biological processes; that relationship is ...
We used the Side effect Resource (SIDER) 4.1 database24to obtain the frequencies of drug side effects and analysed drugs with known Anatomical, Therapeutic and Chemical (ATC) code (see Methods). Following common practice in clinical trials25, we used five frequency classes to quantify the occurr...
Processing SIDER 4.1: the side effect resource rephetiodrugside-effectcompoundsidersider4 UpdatedFeb 3, 2016 Jupyter Notebook A type-safe alternative to redux-saga. // Using `yield*` in `finally` is currently broken in Babel / ES spec, as it will terminate the generator completely. ...
The meaning of SIDE RELIEF ANGLE is the angle between the part of the flanks of a cutting tool below the cutting edge and a plane perpendicular to the base.
Kuhn M, Campillos M, Letunic I, Jensen L, Bork P: A side effect resource to capture phenotypic effects of drugs. Mol Syst Biol 2010, 6: 343. Article PubMed Central PubMed Google Scholar Chen B, Wild D, Guha R: PubChem as a Source of Polypharmacology. Journal of chemical information...
side effect an additional (often bad) effect of a drug etc. These pills have unpleasant side effects.efecto secundarioˈsidelight noun a light fixed to the side, or at the side of the front or back, of a car, boat etc. He switched his sidelights on when it began to get dark. luz...
A side effect resource to capture phenotypic effects of drugs. Mol Syst Biol 6, 343; 10.1038/msb.2009.98 (2010). Article PubMed PubMed Central Google Scholar Wang, Y. et al. PubChem: a public information system for analyzing bioactivities of small molecules. Nucleic Acids Res 37, W623–...
Protein target side effects are inferred from drug-side effect relations provided by the SIDER2 database (http://sideeffects.embl.de/)43. SIDER2 has 99,423 drug-side effect pairs involving 996 drugs and 4,192 distinct side effects (~100 side effects/drug). Predicted drug-target relations ar...