Systemic and ocular complications are seen infrequently in patients with sickle cell trait. In the presence of concomitant systemic diseases or trauma, however, marked retinopathy can occur. The presence of ret
An aetiological workup was done to rule out infective endocarditis, tuberculosis, diabetes, and other immunocompromised conditions. Haemoglobulin electrophoresis showed sickle cell trait. Twenty months later, the patient is currently completely asymptomatic. Conclusion Although a rare entity, fungal splenic ...
Sickle cell disease (SCD) is a group of genetic disorders in which an abnormal Hb molecule (Hb S) transforms RBCs into sickle-shaped cells, resulting in chronic anemia, vasoocclusive episodes, pain, and organ damage. Sickle cell trait, which is the heterozygous condition, is the only 1 of...
RJ Adams, FT Nichols Sickle cell anemia, sickle cell trait and thalassemia PJ Vinken, GW Bruyn, HL Klawans, JF Toole (Eds.), Vascular Diseases Part 3. Vol. 55 of Handbook of Clinical Neurology, Elsevier Science, Amsterdam (1989) Google Scholar 3 SG Pavlakis Neurologic complications of sickl...
This cohort study evaluates whether African American individuals with sickle cell trait have a higher incidence of myocardial infarction or composite
"I was aware that I had this sickle cell trait, but their father was not aware that he had the trait. They do the newborn screenings now for all children, and that's how we found out that he had sickle cell disease," Stacy said. "He was in the NICU st...
Both her parents are consanguineous and have the sickle cell trait, whereas all her siblings are sickle cell-negative on the basis of routine screening. The patient had no history of hypertension, diabetes, or other conditions of medical concern; no history of previous surgeries; and no history...
Slightly decreased Hb A; Moderate amount Hb S (about 40%)Sickle cell traitOne gene copy for Hb S (heterozygous) Majority Hb S; Increased Hb F (up to 10%); No Hb ASickle cell diseaseTwo gene copies for Hb S (homozygous) Is there anything else I should know?
cells in the distal portion of capillaries, and dilatation and thinning of the proximal segments of the vessels [321]. Visual acuity is not affected. The “comma sign” vessels in conjunctiva are an excellent diagnostic tool for sickle cell disease, but they are absent in sickle cell trait. ...
Systemic workup was negative except for protein electrophoresis, which showed sickle cell trait, and HbA1C was 7.8%. Later, atrophic macular changes with a pale optic disc were observed, and BCVA was reduced to light perception. CRAO in young patients amounts to diverse causes, which require ...