Sickle cell disease: Guideline and overviewNo abstract is available for this article.doi:10.1002/ajh.2830470228NoneWiley Subscription Services, Inc., A Wiley CompanyAmerican Journal of Hematology
Clinical practice guidelines on sickle cell disease stem cell transplantation by the American Society of Hematology (ASH) were published in September 2021 in Blood Advances.[1] For patients with sickle cell disease who have had an overt stroke or who have abnormal transcranial Doppler ultrasound ...
PRIMER Sickle cell disease Gregory J. Kato1, Frédéric B. Piel2, Clarice D. Reid3, Marilyn H. Gaston4, Kwaku Ohene‑Frempong5, Lakshmanan Krishnamurti6, Wally R. Smith7, Julie A. Panepinto8, David J. Weatherall9, Fernando F. Costa10 and Elliott P. Vichin...
Meaning Efforts to increase the dissemination and implementation of sickle cell disease treatment guidelines, in particular as they relate to the antibiotic treatment of children hospitalized with acute chest syndrome, are warranted. Abstract Importance Acute chest syndrome (ACS) is a common, serious com...
American Society of Hematology 2020 guidelines for sickle cell disease: Prevention, diagnosis, and treatment of cerebrovascular disease in children and adultsAnemia-Clinical: Sickle cell anemiaRED CELLSBackground Central nervous system (CNS) complications are among the most common, devastating sequelae of...
Sickle cell disease (SCD), which affects approximately 100,000 individuals in the USA and more than 3 million worldwide, is caused by mutations in the βb globin gene that result in sickle hemoglobin production. Sickle hemoglobin polymerization leads to
Sickle Cell Disease (Clinical) Sickle cell disease (SCD) is a group of genetic disorders in which an abnormal Hb molecule (Hb S) transforms RBCs into sickle-shaped cells, resulting in chronic anemia, vasoocclusive episodes, pain, and organ damage. Sickle cell trait, which is the heterozygous...
Genome editing and stem cell therapy pave the path for new treatment of sickle-cell disease Sickle-cell disease (SCD), also known as sickle-cell anemia, is a hereditary blood disorder characterized by the presence of abnormal hemoglobin, the oxyge... MK Randolph,W Zhao - 《Stem Cell ...
Treatment Prognosis What is sickle cell disease (SCD)? Sickle cell disease is a hereditary condition that causes red blood cells to be deformed. Sickle cell anemia (sickle cell disease) is a disorder of the blood caused by inherited abnormal hemoglobin (the oxygen-carrying protein within the...
It's estimated that people with sickle cell disease have a life expectancy that's 20 years shorter than average. With optimal treatment, people with sickle cell disease can live six decades or more. With improved treatments, survival rates and quality of life for people with the disease are ...